TASF Fluorination for Preparing Alkyl Fluorides

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Jinbo Hu Teruo Umemoto  Editors

Fluorination

Synthetic Organofluorine Chemistry

Series Editors Jinbo Hu Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai, China Teruo Umemoto Zhejiang Jiuzhou Pharmaceutical Co., Ltd R&D Center Taizhou, China

This reference work is the first comprehensive encyclopedia covering various methodologies for the synthesis of organofluorine compounds to date. The contents include both conventional and newly developed synthetic methods, with an emphasis on their applications to the synthesis of useful fluorinated molecules. As such, it provides an authoritative and comprehensive reference guide for all researchers interested in synthetic organofluorine chemistry and its applications. The whole series will be published online first, allowing the content to be continuously updated.

Jinbo Hu • Teruo Umemoto Editors

Fluorination With 946 Figures and 42 Tables

Editors Jinbo Hu Key Laboratory of Organofluorine Chemistry Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences Shanghai, China

Teruo Umemoto Zhejiang Jiuzhou Pharmaceutical Co., Ltd R&D Center Taizhou, China

ISBN 978-981-10-3895-2 ISBN 978-981-10-3896-9 (eBook) ISBN 978-981-10-3897-6 (print and electronic bundle) https://doi.org/10.1007/978-981-10-3896-9 © Springer Nature Singapore Pte Ltd. 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

Preface

Driven by the ever-increasing demand for fluorinated organic compounds in pharmaceuticals, agrochemicals, and advanced materials, past years have witnessed the flourishing development of synthetic organofluori