Teriflunomide
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Pulmonary hypertension: case report A 26-year-old man developed pulmonary hypertension during treatment with teriflunomide for multiple sclerosis. The man presented with acute right heart failure secondary to pulmonary hypertension. He had a history of multiple sclerosis and unspecified intolerance to interferon-beta-1a. Eight months prior to presentation, he started receiving teriflunomide [route and dosage not stated]. At current presentation, echocardiogram revealed pulmonary hypertension associated with severe tricuspid insufficiency. The chest CT angiograph ruled-out parenchyma abnormalities or pulmonary thromboembolism. The man was hospitalised and treatment with teriflunomide was discontinued. He received unspecified treatment for primary pulmonary hypertension and was discharged [duration of treatment to reactions onsets not stated and outcome not stated]. Lopez Moreno Y, et al. Secondary pulmonary hypertension in a patient with multiple sclerosis treated with teriflunomide: A case report. European Journal of Neurology 27 803499008 (Suppl. 1): 983 (plus poster) abstr. EPO2351, May 2020. Available from: URL: http://doi.org/10.1111/ene.14308 [abstract]
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Reactions 29 Aug 2020 No. 1819
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