Textbook of Assisted Reproduction
Groundbreaking, comprehensive, and developed by a panel of leading international experts in the field, Textbook of Assisted Reproduction provides a multidisciplinary overview of the diagnosis and management of infertility, which affects 15% of all couples
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Textbook of Assisted Reproduction
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Textbook of Assisted Reproduction
Gautam Nand Allahbadia • Baris Ata Steven R. Lindheim • Bryan J. Woodward Bala Bhagavath Editors
Textbook of Assisted Reproduction
Editors Gautam Nand Allahbadia Consultant Reproductive Endocrinology & IVF Millennium Medical Center MMC IVF Dubai Health Care City Dubai UAE Bourn Hall Fertility Clinic
Baris Ata McGill Reproductive Center Royal Victoria Hospital Women’s Pav Montreal QC Canada
Jumeira Dubai UAE
Bryan J. Woodward X&Y Fertility Leicester UK
Steven R. Lindheim Department of Obstetrics and Gynecology Wright State University Boonshoft School of Medicine Dayton, OH USA
Bala Bhagavath School of Medicine and Dentistry University of Rochester Medical Center Newyork USA
ISBN 978-981-15-2376-2 ISBN 978-981-15-2377-9 (eBook) https://doi.org/10.1007/978-981-15-2377-9 © Springer Nature Singapore Pte Ltd. 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Thank you to all of the healthcare workers who selflessly give themselves to others. Your work is truly incredible and does not go unnoticed. You are true heroes of the COVID-19 crisis that stopped our world, and this book is dedicated to your hard work and sacrifices in the front line helping people.
Foreword
It is more than 60 years since we learned how to stimulate the ovary and the testis and more than 40 years that IVF was introduced. These two events together with the development of the clinical use of gonadotropins, GnRH agonists, and antagonists allowed us to help more than 11 million couples to have children. However, there is still much to learn to improve patient pathways to overcome infertility. According