The Alkali Metal Ions: Their Role for Life

MILS-16 provides an up-to-date review of the impact of alkali metal ions on life. Their bioinorganic chemistry and analytical determination, the solid state structures of bio-ligand complexes and the properties of alkali metal ions in solution in the cont

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Astrid Sigel Helmut Sigel Roland K.O. Sigel Editors

The Alkali Metal Ions: Their Role for Life

Metal Ions in Life Sciences Volume 16

Series editors Astrid Sigel Helmut Sigel Roland K.O. Sigel

More information about this series at http://www.springer.com/series/8385

Astrid Sigel • Helmut Sigel • Roland K.O. Sigel Editors

The Alkali Metal Ions: Their Role for Life

Editors Astrid Sigel Department of Chemistry Inorganic Chemistry University of Basel Spitalstrasse 51 CH-4056 Basel, Switzerland [email protected]

Helmut Sigel Department of Chemistry Inorganic Chemistry University of Basel Spitalstrasse 51 CH-4056 Basel, Switzerland [email protected]

Roland K.O. Sigel Department of Chemistry University of Zürich Winterthurerstrasse 190 CH-8057 Zürich, Switzerland [email protected]

ISSN 1559-0836 ISSN 1868-0402 (electronic) Metal Ions in Life Sciences ISBN 978-3-319-21755-0 ISBN 978-3-319-21756-7 (eBook) DOI 10.1007/978-3-319-21756-7 Library of Congress Control Number: 2015958773 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Cover illustration: Cover figure of the MILS series since Volume 11: RNA-protein interface of the Ile-tRNA synthetase complex held together by a string of Mg2+ ions, illustrating the importance of metal ions in both the protein and the nucleic acid world as well as connecting the two; hence, representing the role of Metal Ions in Life Sciences. tRNA synthetases are not only essential to life, but also serve as a target for novel classes of drugs making such RNA-protein complexes crucial also for the health sciences. The figure was prepared by Joachim Schnabl and Roland K. O. Sigel using the PDB coordinates 1FFY. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)

Historical Development and Perspectives of the Series Metal Ions in Life Sciences*

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