The Devlopment of the Perineum in the Human A Comprehensive Histolog
For over a century, the development of the perineum has received ample attention because of the striking complexity of its formation and malformation. In the prolonged disputes at this subject, normal and abnormal development became intricately interwoven
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Vol. 177
Editors F. Beck, Melbourne B. Christ, Freiburg F. Clasc, Madrid D. E. Haines, Jackson H.-W. Korf, Frankfurt W. Kummer, Gießen E. Marani, Leiden R. Putz, Mnchen Y. Sano, Kyoto T. H. Schiebler, Wrzburg K. Zilles, Dsseldorf
S.C.J. van der Putte
The Devlopment of the Perineum in the Human A Comprehensive Histological Study with a Special Reference to the Role of the Stromal Components
With 46 Figures
S. C. J. van der Putte Department of Pathology University Medical Centre Utrecht P.O. Box 85500, 3508 GA Utrecht, The Netherlands e-mail: [email protected]
Library of Congress Control Number: 2004102481 ISSN 0301-5556 ISBN 3-540-21039-3 Springer Berlin Heidelberg New York This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. Springer is a part of Springer Science+Business Media springeronline.com Springer-Verlag Berlin Heidelberg 2005 Printed in Germany The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publisher cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Editor: Dr. Rolf Lange, Heidelberg, Germany Desk editor: Anne Clauss, Heidelberg, Germany Production editor: Andreas Gsling, Heidelberg, Germany Cover design: design & production GmbH, Heidelberg, Germany Typesetting: Strtz AG, Wrzburg, Germany Printed on acid-free paper 27/3150/ag – 5 4 3 2 1 0
For Marijke
Acknowledgements
I would like to thank the technicians of the laboratories of histopathology and immunohistochemistry for their technical help and wish to acknowledge in particular the contribution of Mr. H. Sakkers, J.L. Hof, W.J.M. Hermsen, and J.A.S. van Ginkel. I am most grateful to Mr. D.F. van Wichen for his great help in preparing the illustrations and to Mrs. I.L. van Rooijen for her assistance in the preparation of the manuscript. I also wish to express my appreciation to my colleagues Prof. Dr. J. Huber, Drs. G. van Noort (Streeklaboratorium Pathologie, Enschede), Dr. P.G.J. Nikkels, and Dr. W.G.M. Spliet for providing the many specimens which were essential for this investigation. I gratefully acknowledge the generosity of the Department of Anatomy and Embryology of the University of Amsterdam (Prof. D
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