The effect of multiple-inflation balloon aortic valvuloplasty
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ORIGINAL ARTICLE
The effect of multiple‑inflation balloon aortic valvuloplasty Akihide Konishi1 · Masamichi Iwasaki2 · Takashi Omori1 · Toshiro Shinke3 Received: 19 January 2020 / Accepted: 15 May 2020 © Springer Japan KK, part of Springer Nature 2020
Abstract Recent improvements of balloon aortic valvuloplasty (BAV) devices and procedures have provided improved outcomes, but it is not clear whether the multiple-inflation BAV technique is effective in patients with symptomatic severe aortic valve stenosis (AS). We conducted an analysis of the impact of multiple-inflation BAV (at least 6 times inflation) on the mean aortic valve area (AVA) and mean aortic valve pressure gradient (AV-PG) in patients with symptomatic severe aortic stenosis as compared with conventional BAV (from single to three times inflation). We identified two studies of multiple-inflation BAV with antegrade approach using Inoue-balloon catheter (425 patients) and four studies of conventional BAV (170 patients) with retrograde approach. Using a random intercept model, we found that multiple-inflation BAV significantly increased mean AVA (mean difference (MD) [95% indicates confidence interval (CI)] = 0.25 [0.16–0.34], P
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