The effect of vitamin D on restless legs syndrome: prospective self-controlled case study
- PDF / 318,602 Bytes
- 6 Pages / 595.276 x 790.866 pts Page_size
- 20 Downloads / 192 Views
NEUROLOGY • ORIGINAL ARTICLE
The effect of vitamin D on restless legs syndrome: prospective self-controlled case study Mesude Tutuncu 1
&
Melih Tutuncu 2
Received: 6 May 2019 / Revised: 18 November 2019 / Accepted: 22 November 2019 # Springer Nature Switzerland AG 2019
Abstract Purpose To evaluate the effect of vitamin D on severity of restless legs syndrome in patients with idiopathic restless legs syndrome (RLS). Methods Patients with idiopathic RLS completed questionnaires including the International Restless Legs Severity Scale (IRLSS) and were evaluated for vitamin D deficiency. Patients with deficiency of vitamin D were treated with 50,000 units per week for 2 months. At the end of the 2 months, vitamin D levels were re-measured and disease severity was re-evaluated in patients who reached adequate vitamin D level. Subgroups of IRLSS questionnaire were also analyzed. Results Of 35 patients enrolled, 21 (60%) had vitamin D deficiency and received vitamin D therapy. In 2 patients, vitamin D levels did not rise to sufficient levels with supplementation and these 2 patients were excluded from analysis. The remaining 19 patients showed vitamin D levels increased from 13.2 ± 4.0 to 42.8 ± 9.6 ng/mL while IRLSS improved from 24.9 ± 5.1 to 21.1 ± 2.9 points (p
Data Loading...
