The gastro-jejunal anastomosis site influences dumping syndrome and weight regain in patients with obesity undergoing La

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ORIGINAL ARTICLE

The gastro‑jejunal anastomosis site influences dumping syndrome and weight regain in patients with obesity undergoing Laparoscopic Roux‑en‑Y Gastric Bypass Rossella D’Alessio1 · Mikiko Watanabe2 · Ida Francesca Gallo1 · Silvia Manfrini3 · Dario Tuccinardi3   · Vincenzo Bruni1 Received: 10 September 2020 / Accepted: 22 September 2020 © Springer Nature Switzerland AG 2020

Abstract Purpose  The Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) is an effective weight loss procedure. The gastro-jejunal (GJ) anastomosis required can be performed on the anterior or posterior gastric pouch wall. No studies have compared these variants in terms of efficacy and onset of dumping syndrome (DS) and weight regain (WR). We aimed at assessing the prevalence of DS in relation to the site of anastomosis together with identifying prognostic factors of DS and WR. Methods  Patients who had undergone LRYGB with anterior (AGJ) or posterior (PGJ) anastomosis in 2010–2019 were retrospectively analyzed. We collected demographic data, medical history and the prevalence of DS evaluated through the Sigstad Score, together with WR data. Results  213 patients were enrolled, of which 51.6% had an AGJ and 48.4% had a PGJ. The mean follow-up time was 81 ± 18 and 27 ± 13 months in the AGJ and PGJ group, respectively (p