The Global Network Maternal Newborn Health Registry: a multi-country, community-based registry of pregnancy outcomes
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RESEARCH
The Global Network Maternal Newborn Health Registry: a multi‑country, community‑based registry of pregnancy outcomes Elizabeth M. McClure1* , Ana L. Garces2, Patricia L. Hibberd3, Janet L. Moore1, Shivaprasad S. Goudar4, Sarah Saleem5, Fabian Esamai6, Archana Patel7, Elwyn Chomba8, Adrien Lokangaka, Antoinette Tshefu, Rashidul Haque9, Carl L. Bose10, Edward A. Liechty11, Nancy F. Krebs12, Richard J. Derman13, Waldemar A. Carlo14, William Petri15, Marion Koso‑Thomas16 and Robert L. Goldenberg17
From Global Network Virtual. 3-15 Septemeber 2020
Abstract Background: The Global Network for Women’s and Children’s Health Research (Global Network) conducts clinical trials in resource-limited countries through partnerships among U.S. investigators, international investigators based in in low and middle-income countries (LMICs) and a central data coordinating center. The Global Network’s objectives include evaluating low-cost, sustainable interventions to improve women’s and children’s health in LMICs. Accurate reporting of births, stillbirths, neonatal deaths, maternal mortality, and measures of obstetric and neonatal care is critical to determine strategies for improving pregnancy outcomes. In response to this need, the Global Network developed the Maternal Newborn Health Registry (MNHR), a prospective, population-based registry of pregnant women, fetuses and neonates receiving care in defined catchment areas at the Global Network sites. This publication describes the MNHR, including participating sites, data management and quality and changes over time. Methods: Pregnant women who reside in or receive healthcare in select communities are enrolled in the MNHR of the Global Network. For each woman and her offspring, sociodemographic, health care, and the major out‑ comes through 42-days post-delivery are recorded. Study visits occur at enrollment during pregnancy, at delivery and at 42 days postpartum. Results: From 2010 through 2018, the Global Network MNHR sites were located in Guatemala, Belagavi and Nagpur, India, Pakistan, Democratic Republic of Congo, Kenya, and Zambia. During this period at these sites, 579,140 pregnant women were consented and enrolled in the MNHR, nearly 99% of all eligible women. Delivery data were collected for 99% of enrolled women and 42-day follow-up data for 99% of those delivered. In this supplement, the trends over
*Correspondence: [email protected] 1 Social, Statistical and Environmental Health Sciences, RTI International, 3040 Cornwallis Rd., Durham, NC 27709, USA Full list of author information is available at the end of the article © The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this arti
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