• PDF / 8,225,345 Bytes
• 865 Pages / 439.42 x 683.15 pts Page_size
• 107 Downloads / 251 Views

DOWNLOAD

REPORT

---

The Handbook of Neuroprotection Second Edition

The Handbook of Neuroprotection

The Handbook of Neuroprotection Second Edition

Kewal K. Jain, MD, FRACS, FFPM Jain PharmaBiotech, Basel, Switzerland

Kewal K. Jain Jain PharmaBiotech Basel, Switzerland

ISBN 978-1-4939-9464-9    ISBN 978-1-4939-9465-6 (eBook) https://doi.org/10.1007/978-1-4939-9465-6 © Springer Science+Business Media, LLC, part of Springer Nature 2011, 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Humana Press imprint is published by the registered company Springer Science+Business Media, LLC, part of Springer Nature. The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.

Preface to the Second Edition

Recognition of the importance of neuroprotection in the management of neurological disorders has steadily increased during the past decade. Considerable progress has been made in this area since the publication of the first edition in 2011. Advances in biotechnology, particularly in cell and gene therapies, have provided several new products for neuroprotection. Some of the old products in clinical trials failed to show efficacy, and these are still retained in the book, while new products in clinical trials are listed. Neuroprotective effect of some drugs approved for other indications is also included as their repurposing is much easier than developing a new drug. This book reviews management of neurological disorders with a focus on neuroprotection and disease modification rather than symptomatic treatment. Neurodegenerative disorders present with considerable damage by the time they are diagnosed, and the aim is to prevent further damage and to reverse some of the damage, which is a bigger challenge. This requires a combination of neuroprotection and neuroregeneration. In the case of acute central nervous system trauma and stroke, immediate damage i