The Life Cycle of the Corpus Luteum

​This book describes the life cycle of a unique endocrine gland that is absolutely essential for the establishment and maintenance of pregnancy in all mammalian species. The corpus luteum is unique because it is formed and destroyed every (non-fertile) re

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The Life Cycle of the Corpus Luteum

The Life Cycle of the Corpus Luteum

Rina Meidan Editor

The Life Cycle of the Corpus Luteum

Editor Rina Meidan The Robert H. Smith Faculty of Agriculture Food and Environment Department of Animal Sciences The Hebrew University of Jerusalem Rehovot, Jerusalem, Israel

ISBN 978-3-319-43236-6 ISBN 978-3-319-43238-0 DOI 10.1007/978-3-319-43238-0

(eBook)

Library of Congress Control Number: 2016953740 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

In this book, The Life Cycle of the Corpus Luteum, we try to provide state-of-the-art knowledge of the corpus luteum, throughout its lifespan, in different species. The corpus luteum is a fascinating endocrine organ that is essential for fertility in mammals. Recent developments in understanding the lifespan of the corpus luteum provide new insights for reproductive biologists and also provide insights into tissue dynamics that translate to other research disciplines (e.g., developmental biology, vascular development, metabolic disorders, cancer). More research on the corpus luteum is needed to provide clinicians, veterinarians, researchers, and livestock producers with the information they require to successfully intervene in human, and other mammalian, fertility outcomes. The ovarian corpora lutea (yellow bodies) were first named by Marcello Malpighi and then described by Regnier de Graaf in the late 1600s. Two centuries later, Prenant suggested that the corpus luteum may serve as a gland that produces substances which regulate pregnancy. This observation was confirmed rapidly by several groups in the early 1900s, and the biologically active substance progesterone was crystallized and characterized nearly simultaneou