The mineralization of polymer electrospun fibrous membranes modified with tourmaline nanoparticles
- PDF / 1,794,326 Bytes
- 11 Pages / 584.957 x 782.986 pts Page_size
- 90 Downloads / 165 Views
FOCUS ISSUE
NANOCRYSTALLINE HIGH ENTROPY MATERIALS: PROCESSING CHALLENGES AND PROPERTIES
The mineralization of polymer electrospun fibrous membranes modified with tourmaline nanoparticles Jinsheng Liang1, Na Hui1, Tianyu Zhao1, Hong Zhang1,a) 1
Key Laboratory of Special Functional Materials for Ecological Environment and Information (Hebei University of Technology), Ministry of Education, Tianjin 300130, China; Institute of Power Source and Ecomaterials Science, Hebei University of Technology, Tianjin 300130, China; and Key Laboratory for New Type of Functional Materials in Hebei Province, Hebei University of Technology, Tianjin 300130, China a) Address all correspondence to this author. e-mail: [email protected] Received: 23 October 2018; accepted: 16 January 2019
As distinctive spontaneous polarization and far-infrared radiation characteristics, the natural mineral tourmaline (TM) has the regulatory effect on crystallization behavior, which possesses potential application in biomimetic mineralization and bone regeneration. In this study, polyurethane (PU) and gelatin (GE) membranes with different adding proportion of TM nanoparticles were prepared via electrospinning. Additionally, the effect of TM nanoparticles on the mineralization process of hydrophobic PU and hydrophilic GE was investigated by immersing the composite TM/PU and TM/GE electrospun membranes in the 10× simulated body fluid (10SBF) at 37 °C for varying periods of time. SEM images confirmed the well-dispersed TM nanoparticles in the PU and GE electrospun fibers. The mineralization deposition was characterized by the SEM, EDS, XRD, and FTIR, and it indicated that two types of calcium phosphate deposits with different Ca/P molar ratios were obtained when TM/PU membranes and TM/GE membranes were incubated in 10SBF. Honeycomb-like hydroxyapatite crystals nucleated and grew faster on TM/PU and TM/GE membranes than the pure PU and GE membranes, respectively. Furthermore, with the increase of the added TM nanoparticles in the composite membranes, more calcium phosphate crystals were precipitated. These results showed that the added TM nanoparticles were able to improve the mineralization of polymer fibrous membranes, which is potential for the composite bone scaffold.
Introduction Bone defects are common diseases, and the number of patients suffering this condition is increasing. Because of the lack of autografts and allografts, synthetic scaffolds have gotten major focus for the bone regeneration of large and load-bearing bone defects [1]. In the last decades, several material classes have been considered for bone scaffolds, including metals, polymers, ceramics, and their combinations. Among these materials, calcium phosphate–based systems have been proven effective for bone graft substitutes because of their compositional similarity to bone mineral, which have shown osteoconductivity, biocompatibility, and bioactivity. Because of the brittle nature of calcium phosphate, metals or hard polymers have been used as a support to avoid mechanical failure,
Data Loading...
