The Modern Pneumatic Tube System Transports with Reduced Speed Does Not Affect Special Coagulation Tests
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TRANSACTIONAL PROCESSING SYSTEMS
The Modern Pneumatic Tube System Transports with Reduced Speed Does Not Affect Special Coagulation Tests Luděk Slavík 1 & Jana Úlehlová 1 & Pavla Bradáčová 1 & Kateřina Chasáková 1 & Antonín Hluší 1 & Miroslava Palová 1 & Alice Entrová 2 Received: 5 May 2020 / Accepted: 15 July 2020 # Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Pneumatic tube transport systems (PTS) for delivery of patient samples to a hemostasis laboratory are often used to reduce turnaround time for vital analyses. PTS in our hospital has the ability to regulate the transport speed in the range of 3–6 m/s with acceleration control technology. We evaluated the effects of PTS transport for routine coagulation tests, platelet function tests and special global coagulation tests. Duplicate samples were collected from 29 patients and 40 healthy individuals. One sample was sent using PTS and the other was carried by personnel to the lab for determination of protrombin time, activated partial thromboplastin time, trombin time, fibrinogen, antitrombin and thrombin generation test. Platelet function was measured by means of a Apact 4004® analyzer using the inductors (ADP, Arachidonic acid and Epinephrine). Samples transported using PTS with normal transport speed 6 m/s does not affect basic coagulation tests (PT, aPTT, FIB, TT and AT), but TGT has significantly altered. The use of PTS with controlled acceleration regulated the increase in thrombin generation from 10% to 3%, which is not statistically signifiant. The use of PTS with controlled acceleration did not show a significant difference even with the highly sensitive method of platelet aggregation. We conclude that PTS with acceleration control with transport speed from 3 to 6 m/s does not affect to platelet activity as measured by LTA and also global coagulation test - TGT. The advantage of PTS transport is very rapid assessment laboratory testing. From the above validation study, it is clear that PTS should always be validated for specialized laboratory methods and appropriately adapted to specific transport conditions. Keywords Pneumatic tube system . Controlled acceleration . Platelet
Backround As the name indicates, pneumatic mail was first used for the transport of mail. Its use spread to medical facilities already in the second half of the previous century. The implementation for the transport of biological material was not easy due to the need to eliminate any effects on the stability of biological material. This article is part of the Topical Collection on Transactional Processing Systems * Luděk Slavík [email protected] 1
Department of Hemato-Oncology, Palacký University Faculty of Medicine and Dentistry and University Hospital Olomouc, Olomouc, Czech Republic
2
Department of Blood Transfusion, University Hospital Olomouc, Olomouc, Czech Republic
Pneumatic systems based on a simple connection of two endpoints with an air tube system with differential pressure have been used to transport samples between operating thea
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