The Present and Future Burden of Contact Dermatitis from Acrylates in Manicure

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Contact Dermatitis (A Gimenez-Arnau, Section Editor)

The Present and Future Burden of Contact Dermatitis from Acrylates in Manicure Marı´a-Elena Gatica-Ortega1,* Marı´a-Antonia Pastor-Nieto2,3 Address *,1 Dermatology Department, University Hospital Complex of Toledo, Carretera de Cobisa s/n, 45071, Toledo, Spain Email: [email protected] 2 Dermatology Department, University Hospital of Guadalajara, Guadalajara, Spain 3 Alcalá de Henares University, Alcalá de Henares, Madrid, Spain

Published online: 18 August 2020 * Springer Nature Switzerland AG 2020

This article is part of the Topical Collection on Contact Dermatitis Keywords Allergic contact dermatitis I Occupational I Acrylates I Methacrylates I Acrylic nails I Nail polish I Long-lasting nail polish I Cosmetics I Medical devices

Abstract Purpose of Review (Meth)acrylates are chemical compounds used in a wide variety of settings such as nail esthetics and the medical field. A progressive increase in the frequency of acrylate-induced sensitization likely caused by the popularity and widespread use of semi-permanent polishes has been described. Recent Findings Several factors contribute to such scenario including the insufficient training of beauticians regarding the risks posed by the manipulation of acrylate-based manicure materials, the fact that some consumers end up self-applying these products at home, and the poor training of the general dermatologist on the specific clinical features of contact allergy to acrylates in manicure products (often misdiagnosed as psoriasis and unnecessarily treated with immunosuppressants). Knowledge of the different techniques and materials used allows the clinician to understand the characteristics and distribution of the lesions. In some cases, sensitization to acrylates from manicure, a merely esthetic procedure, has been described to cause contact dermatitis to medical devices containing acrylates. Summary Information regarding the risks, preventive measures, protection equipment, and training should be delivered to consumers and professionals respectively; the commercialization of these materials for the general public should be regulated and general dermatology practitioners trained to diagnose and manage these patients more efficiently.

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Contact Dermatitis (A Gimenez-Arnau, Section Editor)

Introduction Acrylates and methacrylates, hereby referred to as (meth)acrylates, are formed by the spontaneous or ultraviolet (UV)-induced polymerization of monomers containing an acrylic acid–derived or methacrylic acid–derived acryl group (acrylates or methacrylates respectively) [1••]. Polymers result from the combination of monomers. (Meth)acrylic polymers are extremely versatile. Their presence is ubiquitous, being widely spread substances contained in an extensive scope of applications (Table 1). (Meth)acrylic monomers are responsible for most of the allergic reactions due to (meth)acrylates. Their low molecular weight allows them to penetrate the skin, thus causing the sensitization and the allergic elicitati