The psoas muscle density as a predictor of postoperative complications and 30-day mortality for acute mesenteric ischemi
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SPECIAL SECTION: INTESTINAL ISCHEMIA
The psoas muscle density as a predictor of postoperative complications and 30‑day mortality for acute mesenteric ischemia patients Shou‑Liang Miao1 · Xiao‑Ning Ye2 · Ting‑Ting Lin1 · Yi‑Hui Qiu3 · Jing‑Yong Huang3 · Xiang‑Wu Zheng1 · Fan‑Feng Chen3 Received: 15 May 2020 / Revised: 9 August 2020 / Accepted: 21 August 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Objective Low muscle mass and quality is associated with poor surgical outcomes. Psoas muscle density (PMD)is a validated surrogate for muscle quality that can be easily measured from a clinical computed tomography (CT) scan. The objective of this study was to investigate the association between PMD and short-term postoperative outcomes in patients with acute mesenteric ischemia (AMI). Methods From April 2006 and September 2019, the clinical data of all patients who underwent surgical intervention with a preoperative diagnosis of AMI and had preoperative non-contrast CT images available were retrospectively reviewed. PMD was measured by CT at the third lumbar vertebra. The lowest quartile of PMD for men and women in all patients was used as sex-specific cut-off values for low PMD. Univariate and multivariate analyses evaluating risk factors of postoperative complications and 30-day mortality were performed. Results The cohort consisted of 88 patients with a mean age of 58.8 ± 16.2 years, of whom 21 (23.9%) patients had low PMD based on the diagnostic cut-off values (40.5 HU for men and 28.4 HU for women), 35 (39.8%) patients developed complications within 30 days of the operation, and 10 (11.3%) patients died within 30 days of surgery. Low PMD patients had a higher risk of postoperative complications and 30-day mortality than patients without low PMD patients. In a multivariate analysis, low PMD and low psoas muscle area (PMA) were independent predictors of postoperative complications. However, only low PMD remained an independent risk factor for 30-day mortality. Conclusions Preoperative assessment of the PMD on CT can be a practical method for identifying AMI patients at risk for postoperative complications and 30-day mortality. Keywords Acute mesenteric ischemia · Morbidity · Mortality · Psoas muscle density
Introduction Shou-Liang Miao and Xiao-Ning Ye have participated equally to this work and should share “first authorship”. Xiang-Wu Zheng and Fan-Feng Chen have participated equally to this work and should share “corresponding authorship”.
Acute mesenteric ischemia (AMI) is an infrequent, but complicated, life-threatening condition. Despite the advances in diagnosis of AMI, morbidity and mortality rates remain high [1]. Fortunately, outcomes in terms of mortality and
* Xiang‑Wu Zheng [email protected]
2
The First Clinical Medical Institute, Wenzhou Medical University, Wenzhou, Zhejiang, China
* Fan‑Feng Chen [email protected]
3
Department of Vascular Surgery, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang, Ouhai District, Wenzhou 325015
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