The role of the comprehensive complication index for the prediction of survival after liver transplantation
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ORIGINAL ARTICLE
The role of the comprehensive complication index for the prediction of survival after liver transplantation Quirino Lai1 · Fabio Melandro1 · Greg Nowak2 · Daniele Nicolini3 · Samuele Iesari4,5 · Elisa Fasolo6 · Gianluca Mennini1 · Antonio Romano2 · Federico Mocchegiani3 · Kevin Ackenine4 · Marina Polacco6 · Laura Marinelli3 · Olga Ciccarelli4 · Giacomo Zanus6 · Marco Vivarelli3 · Umberto Cillo6 · Massimo Rossi1 · Bo‑Göran Ericzon2 · Jan Lerut4 Received: 21 April 2020 / Accepted: 30 August 2020 © The Author(s) 2020
Abstract In the last years, several scoring systems based on pre- and post-transplant parameters have been developed to predict early post-LT graft function. However, some of them showed poor diagnostic abilities. This study aims to evaluate the role of the comprehensive complication index (CCI) as a useful scoring system for accurately predicting 90-day and 1-year graft loss after liver transplantation. A training set (n = 1262) and a validation set (n = 520) were obtained. The study was registered at https: //www.Clinic alTri als.gov (ID: NCT03723317). CCI exhibited the best diagnostic performance for 90 days in the training (AUC = 0.94; p
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