The survival outcomes and prognosis of stage IV non-small-cell lung cancer treated with thoracic three-dimensional radio
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RESEARCH
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The survival outcomes and prognosis of stage IV non-small-cell lung cancer treated with thoracic three-dimensional radiotherapy combined with chemotherapy ShengFa Su1? , YinXiang Hu1? , WeiWei Ouyang1? , Zhu Ma1, Bing Lu1,2*, QingSong Li1, HuiQin Li1, ZhiYong Wang1 and Yu Wang1
Abstract Background: The impact of thoracic three-dimensional radiotherapy on the prognosis for stage IV non-small-cell lung cancer is unclear. This study is to investigate survival outcomes and prognosis in patients with stage IV non-small cell lung cancer (NSCLC) treated with thoracic three-dimensional radiotherapy and systemic chemotherapy. Methods: Ninety three patients with stage IV NSCLC had received at least four cycles of chemotherapy and thoracic three-dimensional radiotherapy of ≥40 Gy on primary tumors. The data from these patients were retrospectively analyzed. Results: Of the 93 patients, the median survival time (MST) was 14.0 months, and the 1, 2, and 3-year survival rates were 54.8%, 20.4%, and 12.9%, respectively. The MST of patients received radiation dose to primary tumor ≥63Gy and
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