Time-Resolved High-Resolution Angiography Combining Arterial Spin Labeling and Time-of-Flight Imaging
- PDF / 842,268 Bytes
- 10 Pages / 439.37 x 666.142 pts Page_size
- 33 Downloads / 176 Views
Applied Magnetic Resonance
ORIGINAL PAPER
Time‑Resolved High‑Resolution Angiography Combining Arterial Spin Labeling and Time‑of‑Flight Imaging Thomas Lindner1,2 · Olav Jansen2 · Michael Helle3 Received: 6 May 2020 / Revised: 20 July 2020 / Accepted: 18 September 2020 © The Author(s) 2020
Abstract A strategy to combine two non-contrast-enhanced magnetic resonance angiography techniques is presented. It is based on arterial spin-labeled magnetic resonance imaging to visualize the arterial system at different time points to obtain information about hemodynamic properties in conjunction with a high-resolution time-offlight angiography acquisition. The temporal information obtained by arterial spin labeling (ASL) is combined with the highly spatial resolved time-of-flight image to obtain information about blood flow. Extracting the information of ASL and timeof-flight-imaging leads to images with high spatial resolution which also give information about the temporal course of blood through the intracerebral vasculature. Furthermore, owing to the properties of ASL, visible venous flow in the time-offlight images can be suppressed. The behavior of vascular filling (i.e. signal changes in the ASL) is investigated and used for further interpretation of the data. Furthermore, the ASL data were down-sampled to find a minimally needed spatial resolution to combine both image types. Up to 1.6 mm isotropic resolution still showed satisfying results rated by two independent readers. In conclusion, a combination of these two different vascular imaging modalities allows to obtain highly spatial and time-resolved images.
1 Introduction A detailed visualization of brain feeding arteries and intracranial vessels is important for the diagnosis of many cerebral diseases including stroke, arterio-venous malformations, aneurysms and others [1]. High spatial resolution magnetic resonance * Thomas Lindner [email protected] 1
Department of Diagnostic and Interventional Neuroradiology, University Hospital HamburgEppendorf, Martinistr. 52, 20246 Hamburg, Germany
2
Department of Radiology and Neuroradiology, University Medical Center Schleswig-Holstein, Kiel, Germany
3
Philips GmbH Innovative Technologies, Research Laboratories, Hamburg, Germany
13
Vol.:(0123456789)
T. Lindner et al.
angiography (MRA) techniques have been developed that allow for the assessment of structural morphology of these vessels. It is, for example, possible to measure the intraluminal diameter in stenotic arteries or to detect small aneurysms [2]. For an advanced diagnosis, however, additional information about the hemodynamics becomes useful [3]. In magnetic resonance imaging (MRI), several acquisition techniques are being used to gather sufficient spatial and temporal information about the cerebral vasculature for a complete diagnosis of the vessel architecture and its hemodynamics [4, 5]. Spatial and temporal information are concluded from different sequences which impedes a correct diagnosis of a variety of diseases, especially when the arterie
Data Loading...
