Towards Offline PET Monitoring at a Cyclotron-Based Proton Therapy Facility

Matthias Würl presents two essential steps to implement offline PET monitoring of proton dose delivery at a clinical facility, namely the setting up of an accurate Monte Carlo model of the clinical beamline and the experimental validation of positron emit

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Towards Offline PET Monitoring at a Cyclotron-Based Proton Therapy Facility Experiments and Monte Carlo Simulations

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Matthias Würl

Towards Offline PET Monitoring at a Cyclotron-Based Proton Therapy Facility Experiments and Monte Carlo Simulations

Matthias Würl Garching, Germany

BestMasters ISBN 978-3-658-13167-8 ISBN 978-3-658-13168-5 (eBook) DOI 10.1007/978-3-658-13168-5 Library of Congress Control Number: 2016932889 Springer Spektrum © Springer Fachmedien Wiesbaden 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer Spektrum imprint is published by Springer Nature The registered company is Springer Fachmedien Wiesbaden GmbH

Acknowledgments

This thesis would not have been possible without the help and support of many people. Above all, I would like to show gratitude to my supervisor, Prof. Dr. Katia Parodi, who has supported me throughout this entire project. Japan, Texas, Heidelberg or in the office - no matter how far away, I could always count on immediate and certainly valuable help. Her way of asking questions always made me think twice about things that seemed clear to me. I am glad to have the opportunity to work at her chair for the next few years. I express my warm thanks to my external supervisor, Dr. Martin Hillbrand, from the Rinecker Proton Therapy Center for his invaluable and kind support and for making this work possible. Hundreds of e-mails and hours of