Transjugular intrahepatic portosystemic shunt through left branch versus right branch of portal vein: a meta-analysis

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Transjugular intrahepatic portosystemic shunt through left branch versus right branch of portal vein: a meta‑analysis Kai Zuo1 · Cong Wang2 · Jun Wang3 · Feng‑Fei Xia4 · Tao Song5  Received: 20 June 2020 / Revised: 11 September 2020 / Accepted: 27 September 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020

Abstract Purpose  To compare the clinical outcomes between patients that underwent transjugular intrahepatic portosystemic shunt (TIPS) via the left and right portal veins (PVs). Materials and methods  All relevant studies in the Pubmed, Embase, and Cochrane Library databases published as of June 2020 were identified by searching, after which RevMan v5.3 was used to conduct the present meta-analysis. Relevant endpoint data were extracted from each study, related to postoperative hepatic encephalopathy (HE) rates, TIPS dysfunction, re-bleeding, and mortality. Results  A total of eight studies were identified as being relevant for inclusion in this meta-analysis. These studies included 2592 total patients suffering from liver cirrhosis that underwent TIPS treatment via the left (n = 1500) or right (n = 1092) PVs. Rates of postoperative HE were significantly lower in the left PV group relative to the right PV group (5.7% vs. 18.1%, OR 0.19; P