Transurethral ventral buccal mucosa graft inlay for treatment of distal urethral strictures: international multi-institu
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ORIGINAL ARTICLE
Transurethral ventral buccal mucosa graft inlay for treatment of distal urethral strictures: international multi‑institutional experience Michael Daneshvar1 · Jay Simhan2 · Stephen Blakely1 · Javier C. Angulo3,4 · Jacob Lucas2 · Craig Hunter5 · Justin Chee6 · Damian Lopez Alvarado7 · Erick Alejandro Ramirez Perez8 · Alosh Madala9 · Juan José de Benito10 · Francisco Martins11 · João Felício11 · Paul Rusilko12 · Brian J. Flynn13 · Dmitriy Nikolavsky1 Received: 6 November 2019 / Accepted: 15 December 2019 © Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Purpose To critically evaluate a multi-institutional patient cohort undergoing single-stage distal urethral repair using a novel transurethral buccal mucosa graft inlay urethroplasty technique (TBMGI). Methods A retrospective multi-institutional review of consecutive patients with fossa navicularis (FN) strictures treated with a single-stage TBMGI technique at 12 institutions from March 2014–March 2018 was performed. Patient demographics, stricture characteristics, clinical and patient-reported outcomes were analyzed. The primary outcomes were stricture recurrence and complications. Secondary outcomes were change in maximum urinary flow rate (Qmax), PVR, and changes in IPSS, SHIM and global response assessment (GRA) questionnaire responses. Descriptive statistical analysis was used for evaluation of outcomes. Results Sixty-eight men met inclusion criteria. Median age and stricture length were 60 years (IQR 48–69) and 2 cm (IQR 2–3), respectively. Most common stricture etiology was lichen sclerosus (34%). Median operative time and EBL were 72 min (IQR 50–120) and 20 mL (IQR 10–43), respectively. Fifty-seven men completed ≥ 12-month follow-up. At a median follow-up of 17 months (IQR 13–22), 54 patients (95%) remained stricture-free. Median Qmax improved from 5 to 18 mL/s (p
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