Treatment of Sleep Comorbidities in Posttraumatic Stress Disorder

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PTSD (SK Creech and LM Sippel, Section Editors)

Treatment of Sleep Comorbidities in Posttraumatic Stress Disorder Janeese A. Brownlow, PhD1,2,* Katherine E. Miller, PhD3 Philip R. Gehrman, PhD, CBSM2,3 Address 1 Department of Psychology, College of Health & Behavioral Sciences, Delaware State University, 1200 North DuPont Highway, Dover, DE, 19901, USA *,2 Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Email: [email protected] 3 Mental Illness Research, Education, and Clinical Center, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA

* Springer Nature Switzerland AG 2020

This article is part of the Topical Collection on PTSD Keywords Posttraumatic stress disorder I Sleep disorders I Sleep disturbances I Psychotherapy I Pharmacotherapy I Comorbidity

Abstract Purpose of the review Sleep disturbances, insomnia and recurrent nightmares in particular, are among the most frequently endorsed symptoms of posttraumatic stress disorder (PTSD). The present review provides a summary of the prevalence estimates and methodological challenges presented by sleep disturbances in PTSD, highlights the recent evidence for empirically supported psychotherapeutic and pharmacological interventions for comorbid sleep disturbances implicated in PTSD, and provides a summary of recent findings on integrated and sequential treatment approaches to ameliorate comorbid sleep disturbances in PTSD. Recent findings Insomnia, recurrent nightmares, and other sleep disorders are commonly endorsed among individuals with PTSD; however, several methodological challenges contribute to the varying prevalence estimates. Targeted sleep-focused therapeutic interventions can improve sleep symptoms and mitigate daytime PTSD symptoms. Recently, attention has focused on the role of integrated and sequential approaches, suggesting that comprehensively treating sleep disturbances in PTSD is likely to require novel treatment modalities.

PTSD (SK Creech and LM Sippel, Section Editors) Summary Evidence is growing on the development, course, and treatment of comorbid sleep disturbances in PTSD. Further, interventions targeting sleep disturbances in PTSD show promise in reducing symptoms. However, longitudinal investigations and additional rigorous controlled trials with diverse populations are needed to identify key features associated with treatment response in order to alleviate symptoms.

Introduction Approximately 87% of posttraumatic stress disorder (PTSD) patients endorse subjective sleep disturbances [1]. There has been extensive growth of the literature on treatment modalities and recommendations for sleep comorbidities in PTSD within the last decade. Sleep disturbances are core features of PTSD and have been considered hallmark symptoms of the disorder [2]. These core sleep disturbances are identified within the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) diagnostic criteria with nightmares or distressing dreams among the intrusion symptom