Treatment-Related Optimism Protects Quality of Life in a Phase II Clinical Trial for Metastatic Renal Cell Carcinoma
- PDF / 209,076 Bytes
- 8 Pages / 595.276 x 790.866 pts Page_size
- 64 Downloads / 160 Views
ORIGINAL ARTICLE
Treatment-Related Optimism Protects Quality of Life in a Phase II Clinical Trial for Metastatic Renal Cell Carcinoma Kathrin Milbury, Ph.D. & Nizar M. Tannir, M.D. & Lorenzo Cohen, Ph.D.
Published online: 6 August 2011 # The Society of Behavioral Medicine 2011
Abstract Background Patients on clinical trials often experience declining quality of life (QOL). Little is known about the psychosocial variables that buffer against decline. Purpose This study aims to examine correlations between psychosocial variables and QOL over the course of a clinical trial in patients with metastatic renal cell cancer. Methods At baseline, 114 participants completed measures of treatment-related optimism, social support, and QOL (Functional Assessment of Cancer Therapy-General). QOL was also assessed 2, 4, and 8 weeks after the start of treatment with low-dose or intermediate-dose interferon. Results QOL decreased significantly in the intermediatedose group but not in the low-dose group (p
Data Loading...
