Trigger Characteristics of EUSIG-Defined Hypotensive Events
Background: Hypotension is a recognized secondary insult after traumatic brain injury (TBI). There are many definitions of hypotension, an often cited example being the Brain Trauma Foundation’s current (2007) “Guidelines for the Management of Severe Tra
- PDF / 290,023 Bytes
- 5 Pages / 595.28 x 790.87 pts Page_size
- 79 Downloads / 198 Views
R. Donald () School of Mathematics and Statistics, University of Glasgow, Glasgow, Scotland, UK e-mail: [email protected], [email protected] T. Howells, P. Enblad, and P. Nilsson Department of Neurosurgery, Uppsala University Hospital, Uppsala, Sweden I. Piper Department of Clinical Physics, Institute of Neurological Sciences, Southern General Hospital, 1345 Govan Road, Glasgow, Scotland G514TF, UK I. Chambers Department of Medical Physics, James Cook University Hospital, Middlesbrough, UK G. Citerio Neurorianimazione, Hospital San Gerardo, Monza, Italy B. Gregson Department of Regional Medical Physics, Newcastle General Hospital, Newcastle, UK K. Kiening and J. Mattern Department of Neurosurgery, Ruprecht-Karls-Universitat Hospital, Heidelberg, Germany A. Ragauskas Head of Telematics (Biomedical) Sc. Lab., Kaunas University of Technology, Kaunas, Lithuania J. Sahuquillo Department of Neurosurgery, Vall d’Hebron University Hospital, Barcelona, Spain R. Sinnott Department of Information Systems, University of Melbourne, Melbourne, Australia A. Stell National eScience Centre, University of Glasgow, Glasgow, Scotland, UK
Abstract Background: Hypotension is a recognized secondary insult after traumatic brain injury (TBI). There are many definitions of hypotension, an often cited example being the Brain Trauma Foundation’s current (2007) “Guidelines for the Management of Severe Traumatic Brain Injury,” which defines hypotension as systolic pressure 100; 5 m*
BPm > 70; 5 m*
BPm > 70; 5 m
CPP > 60; 5 m
BPs > 90; 10 m
BPs > 90; 15 m
Note the * values were estimated as the center did not define this parameter Table 2 Event profile definitions Trigger Clear Profile name BPs (Type 1)
BPm (Type 2)
Both BPs, BPm (Type 3)
BPs
T-BPs-C-BPs-BPm-Enclosed --- (1)
BPs
T-BPs-C-BPs-BPs-Only --- (2)
BPm
T-BPs-C-BPm --- (3)
Both
T-BPs-C-Both --- (4)
BPm
T-BPm-C-BPm-BPs-Enclosed --- (5)
BPm
T-BPm-C-BPm-Only --- (6)
BPs
T-BPm-C-BPs --- (7)
Both
T-BPm-C-Both --- (8)
BPs
T-Both-C-BPs-BPm-Enclosed --- (9)
BPm
T-Both-C-BPm-BPs-Enclosed --- (10)
Both
T-Both-C-Both --- (11)
and the event clear mechanism (BPs and BPm). In Table 2, T = trigger, C = Clear, and --- (x) = Event Profile (Fig. 2).
Data Analysis The method used to initially investigate this problem was to develop a Java-based application called “Data Set Generator” (DSG) to scan the BrainIT database for hypotensive events; this is outlined in the section Java-Based Software. After deciding that investigations should focus on the use of the Edinburgh University Secondary Insult Grades (EUSIG) definitions, the DSG was programmed to classify each event as coming from one of the 11 profiles described in the section Event Profiles. As the results emerged it was decided to verify the findings by using an alternative technique based on SQL and PERL scripts, this is described in the section SQL and PERL Scripts.
Java-Based Software The DSG program is a Java-based application that we have coded for the AvertIT project. It reads a configuration fi
Data Loading...
