Two-year retrospective study of the effect of preemptive kidney transplantation and pretransplant mineral bone factors o
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ORIGINAL ARTICLE
Two‑year retrospective study of the effect of preemptive kidney transplantation and pretransplant mineral bone factors on calcium in post‑kidney transplant recipients Makoto Tsujita1,2 · Norihiko Goto2 · Kenta Futamura2 · Manabu Okada2 · Takahisa Hiramitsu2 · Shunji Narumi2 · Kazuharu Uchida1 · Kunio Morozumi1 · Yoshihiko Watarai2 Received: 10 January 2020 / Accepted: 21 April 2020 © Japanese Society of Nephrology 2020
Abstract Background Preemptive kidney transplantation (PEKT) incidence has recently increased in Japan. The effect of PEKT and mineral bone factors before kidney transplantation (KTx) on long-term calcium (Ca) levels remains unknown. Methods Eighty-one consecutive patients at Nagoya Daini Red Cross Hospital were included in this study (PEKT group with 41 patients and non PEKT group with 40 patients). Ca metabolism, including intact fibroblast growth factor 23 (iFGF23), were measured before KTx and intact parathyroid hormone (iPTH), and corrected Ca (cCa) were measured before KTx and 6 months (M), 12 M, and 24 M after KTx. Results In PEKT group, cCa levels at 24 M were higher from the baseline level. At baseline, cCa levels had a positive correlation with iFGF23 levels (r = 0.51; p
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