Usefulness of dual-layer spectral CT in follow-up examinations: diagnosing recurrent squamous cell carcinomas in the hea
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ORIGINAL ARTICLE
Usefulness of dual‑layer spectral CT in follow‑up examinations: diagnosing recurrent squamous cell carcinomas in the head and neck Koji Takumi1 · Hiroto Hakamada1 · Hiroaki Nagano1 · Yoshihiko Fukukura1 · Yuichi Kumagae1 · Osamu Sakai2 · Takashi Yoshiura1 Received: 30 July 2020 / Accepted: 1 November 2020 © Japan Radiological Society 2020
Abstract Purpose To evaluate the usefulness of dual-energy analyses using dual-layer spectral CT (DLSCT) for diagnosing recurrent lesions of head and neck squamous cell carcinoma (HNSCC). Materials and methods The study population comprised 62 patients with a history of HNSCC. Attenuation values on conventional 120-kVp images and 40-keV virtual monochromatic images (VMIs) and iodine concentration (IC) were compared between recurrent lesions and post-treatment changes or non-recurrent nodes using the Mann–Whitney U test. Receiver-operating characteristic (ROC) analysis was used to assess the ability of attenuation values and IC to diagnose recurrent lesions. Results Attenuation values for 120-kVp and 40-keV images and IC of local recurrent lesions were significantly higher than those of post-treatment changes (p
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