Uterine Adenomyosis
This useful book examines the full spectrum of data available on uterine adenomyosis, covering early to modern literature. The authors look at the recent scientific advancements in the pathophysiology of this disease, giving the reader insight into its di
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Uterine Adenomyosis
Marwan Habiba • Giuseppe Benagiano Editors
Uterine Adenomyosis
Editors Marwan Habiba University Hospitals of Leicester Leicester UK
Giuseppe Benagiano Sapienza University Sapienza Roma Italy
ISBN 978-3-319-13011-8 ISBN 978-3-319-13012-5 DOI 10.1007/978-3-319-13012-5
(eBook)
Library of Congress Control Number: 2015954725 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)
Preface
Over the past few decades, we have witnessed countless advances in bioscience. This is reflected in the range of information published on adenomyosis, as well as in the experimental designs of recent research. However, despite these advances, fundamental questions about the pathophysiology, clinical significance and impact of adenomyosis – a condition originally described more than a century ago – remain unanswered. L. Emge in 1962 credited his teacher, Gideon Wells, for recognising that adenomyosis can elude clinical recognition. The term “elusive” is perhaps as applicable to adenomyosis today as it was in these earlier writings; this is perhaps all the more surprising, given the frequency by which it is identified in uteri removed at hysterectomy. The relatively small body of available literature also reflects that the prevalence of the condition has not been matched by corresponding research interest. Non-invasive diagnosis using modern imaging techniques has fallen short of the expectation that it would enhance clinical management and research and further our understanding of the epidemiology, natural history and pathophysiology of adenomyosis. This may, at least in part, be attributable to the large number of parameters that need to be taken into consideration before well grounded conclusions could be derived from research i
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