Validation of the Clinical COPD questionnaire in Italian language
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Validation of the Clinical COPD questionnaire in Italian language Salvatore Damato*1,2, Chiara Bonatti†2, Vinicio Frigo†2, Silvana Pappagallo1, Rita Raccanelli†2, Claudio Rampoldi†2 and Francesco Rodi†2 Address: 1Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Via Cadore 48, 20052 Monza (MI), Italy and 2Division of Pulmonary Rehabilitation, Ospedale Trabattoni-Ronzoni, Via Verdi, 2 20048 Seregno (MI), Italy Email: Salvatore Damato* - [email protected]; Chiara Bonatti - [email protected]; Vinicio Frigo - [email protected]; Silvana Pappagallo - [email protected]; Rita Raccanelli - [email protected]; Claudio Rampoldi - [email protected]; Francesco Rodi - [email protected] * Corresponding author †Equal contributors
Published: 07 February 2005 Health and Quality of Life Outcomes 2005, 3:9
doi:10.1186/1477-7525-3-9
Received: 07 December 2004 Accepted: 07 February 2005
This article is available from: http://www.hqlo.com/content/3/1/9 © 2005 Damato et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: The development and validation study of the Clinical Chronic Obstructive Disease (COPD) Questionnaire (CCQ) has recently been published in this journal. The CCQ is the first questionnaire that incorporates both clinician and patient guideline goals in the clinical control evaluation of patients with COPD in general clinical practice. The aim of this study is the validation of the CCQ questionnaire in Italian, in specific pulmonary disease clinical practice. Methods: Validity was tested on a population of healthy subjects and patients with COPD, using the Italian validated version of the Short Form Health Survey (SF-36) and guideline recommended routine measurement in COPD patients (FEV1, FVC, BMI and functional dyspnoea). Test-retest reliability was tested by re-administering the CCQ after 2 weeks. Responsiveness was tested by readministering the CCQ after three weeks of hospital pulmonary rehabilitation. Distance walked and Borg breathlessness rating were measured at the end of the six-minute walking test (6 MWT), before and after rehabilitation. Results: Cross-sectional data were collected from 175 subjects (55 healthy; 40 mild-moderate, 50 severe and 25 very severe COPD). Cronbach's alpha was high (0.89). The CCQ scores in patients were significantly worse than in healthy subjects. The CCQ total score in patients with COPD was significantly worse in those with BMI < = 21. Significant correlations were found between the CCQ total score and domains of the SF-36 (rho = -0.43 to rho = -0.72). The correlation between the CCQ and FEV1 % predicted was rho = -0.57. The correlation between the CCQ and MRC was rho = 0.63. Test-retest reliabil
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