Virus Inclusions in Insect Cells

Although the virus diseases of insects have been known for many years, investigation of them has been rather spasmodic and it was not until the development of the electron microscope that our knowledge of these viruses began to expand. There are several d

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L. V. HEILBRUNN

UND

F. WEBER

PHILADELPHIA

GRAZ

MITHERAUSGEBER W. H. ARISZ·GRONINGEN . H. BAUER·WILHELMSHAVEN . J. BRACHET· BRUXELLES • H. G. CALLAN· ST. ANDREWS . R. COLLANDER· HELSINKI • K. DAN·TOKYO . E. FAURE·FREMIET·PARIS . A. FREY·WYSSLlNG·ZORICH· L. GEITLER·WIEN . K. HOFLER·WIEN . M. H. JACOBS· PHILADELPHIA . D. MAZIA·BERKELEY . A. MONROY·PALERMO . J. RUNNSTROM·STOCKHOLM· W. J . SCHMIDT· GIESSEN . S. STRUGGER ·MONSTER

BAND IV

VIR US 3

THE MULTIPLICATION OF VIRUSES 4a

VIRUS INCLUSIONS IN PLANT CELLS 4b

VIRUS INCLUSIONS IN INSECT CELLS 5

ANTIBIOTIKA ERZEUGENDE VIRUS·AHNLICHE FAKTOREN IN BAKTERIEN

WIEN SPRINGER-VERLAG 1958

THE l\IULTIPLICATION OF VIRUSES BY

S.E. LURIA URBANA/ILLINOIS

VIRUS INCLUSIONS IN PLANT CELLS BY

KENNETH M. SMITH CAMBRIDGE

WITH 5 PLATES

VIRUS INCLUSIONS IN INSECT CELLS BY

KENNETH M. SMITH CAMBRIDGE

WITH 16 FIGURES

ANTIBIOTIKA ERZEUGENDE VIRUSA.HNLICHE FAKTOREN IN BAKTERIEN VON

PIERRE FREDERICQ LOTTICH

WIEN SPRINGER-VERLAG 1958

ISBN 978-3-211-80488-9

ISBN 978-3-7091-5461-8 (eBook)

DOI 10.1007/978-3-7091-5461-8

ALLE RECHTE, INSBESONDERE DAS DER UBERSETZUNG IN FREMDE SPRACHEN, VORBEHALTEN. OHNE AUSDRUCKLICHE GENEHMIGUNG DES VERLAGES 1ST ES AUCH NICHT GESTATTET, DIESES BUCH ODER TEILE DARAUS AUF PHOTOMECHANISCHEM WEGE (PHOTOKOPIE, MIKROKOPIE) ZU VERVIELFALTlGEN.

©

BY SPRINGER·VERLAG IN VIENNA 1958.

Protopiasmatoiogia IV. Virus 3. The Multiplication of Viruses

The Multiplication of Viruses 1 By

s. E.

LURIA

Department of Bacteriology, University of Illinois, Urbana, IllinoL'l

Dedicated to Professor Giuseppe Levi on his 85th birthday, as a token of respect and affection

Contents Page

Problems of Virus Multiplication . Multiplication of Bacterial Viruses (Bacteriophages) Early phases of phage-cell interaction The vegetative reproduction cycle . . . . . . . Lysogeny . . . . . . . . . . . . . . . . . . .

2 4

4 6

1'7

Multiplication of Viruses in Cells of Vertebrate Hosts Properties of the viruses . . . . . . . . . General course of animal virus growth . Stages in virus-cell interaction . . . . . . . fate of the host cells in virus multiplication Multiple and mixed infection . . . . . . . Persistent virus-host association in vertebrate cells

21 21 25 26

Multiplication of Viruses in Insects . . . . . . . . . Insect-pathogenic viruses . . . . . . . . . . . . .Viruses of vertebrates and of plants in their insect vectors The CO2 sensitivity agent of Drosophila . . . . . . . . .

40 40

34

35 37

41

42

Mulvlplication of Plant Viruses . . . . . . . . . . . . . . The nature of the infectious material and the initiation of infection Overall course of virus multiplication Persistent infections with plant viruses The relation of the virus to the cell

43 44

References . . . . . . . . . . . . . .

54

46 51 51

1 Aided by grants from the American Cancer Society, Inc. and the Univers'ity Research Board, University of Illinois.

l'rotop\nsmnto\ogin IV, 3, 4 n, 4 II, und 5

IV,3: S. E.

2

LURIA,

The Multiplication of Viruses

List of abbreviations AMPS = d-Amino-2