Vitamin-K

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Lack of efficacy: case report In a retrospective study involving 75 babies, an 84-days-old infant [sex not stated] was described, who exhibited lack of efficacy during treatment with vitamin K for suspected vitamin-K deficiency bleeding. The infant, who had received BCG vaccine at birth, developed injection site bleeding along with bulging fontanelle, stiffness and seizure. The infant was suspicious for vitamin K deficiency bleeding and received treatment with vitamin K [route and dosage not stated] along with blood transfusion. However, the patient continued to have mild bleeding, which was considered as lack of efficacy of vitamin K. Eventually, the patient died [immediate cause of death not stated]. Pradhan R, et al. Vaccine safety surveillance informs public health policy beyond immunization: A case-series on bleeding following vaccination, Nepal, 2016-2018. Vaccine 803514784 38: 6320-6326, No. 40, 11 Sep 2020. Available from: URL: http://doi.org/10.1016/j.vaccine.2020.07.035

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Reactions 14 Nov 2020 No. 1830

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