Weight Loss After Bariatric Surgery in Morbidly Obese End-Stage Kidney Disease Patients as Preparation for Kidney Transp
- PDF / 292,287 Bytes
- 7 Pages / 595.276 x 790.866 pts Page_size
- 55 Downloads / 214 Views
ORIGINAL CONTRIBUTIONS
Weight Loss After Bariatric Surgery in Morbidly Obese End-Stage Kidney Disease Patients as Preparation for Kidney Transplantation. Matched Pair Analysis in a High-Volume Bariatric and Transplant Center Małgorzata Dobrzycka 1 & Monika Proczko-Stepaniak 1 & Łukasz Kaska 1 & Maciej Wilczyński 1 & Alicja Dębska-Ślizień 2 & Jarosław Kobiela 1
# The Author(s) 2020
Abstract Background The number of morbidly obese kidney transplant candidates is growing. They have limited access to kidney transplantation and are at a higher risk of postoperative complications. Bariatric surgery is considered as a safe weight loss method in those patients. Objectives Matched pair analysis was designed to analyze the preparatory and postoperative weight loss after bariatric procedures in end-stage kidney disease (ESKD) and non-ESKD morbidly obese patients. Methods Twenty patients with ESKD underwent bariatric surgery in our Centre of Excellence for Bariatric and Metabolic Surgery between 2015 and 2019 (nine one-anastomosis gastric bypasses, nine Roux-en-Y gastric bypasses, and two sleeve gastrectomies). They were compared with matched pairs from a dataset of 1199 morbidly obese patients without ESKD. Data on demographic factors and comorbidities was recorded. BMI was obtained at the start of the preparatory period preceding the bariatric procedure, at the time of procedure, and during the 1-year follow-up. Results The ESKD and non-ESKD patients did not differ significantly in preoperative weight loss (13.00 ± 11.69 kg and 15.22 ± 15.96 kg respectively, p = 0.619). During the 1-year follow-up, the weight loss was similar to the non-ESKD group. In the first 3 months, faster weight loss in ESKD was observed. Initial and follow-up BMI values did not differ significantly between groups. We demonstrated that obese patients with ESKD can lose weight as effectively as non-ESKD patients. Conclusion Morbidly obese ESKD patients have an equal weight loss to patients without ESKD. Bariatric surgery could improve access to kidney transplantation and may potentially improve transplantation outcomes of obese patients with ESKD. Keywords Bariatric surgery . Kidney transplantation . End-stage kidney disease . Weight loss
Introduction Obesity is a growing problem worldwide. The prevalence of obesity has doubled since 1980, and now, nearly a third of the world’s population is classified as overweight or obese.
* Małgorzata Dobrzycka [email protected] 1
Department of General, Endocrine and Transplant Surgery, Medical University of Gdansk, Gdansk, Poland
2
Department of Nephrology and Transplant Medicine, Medical University of Gdansk, Gdansk, Poland
Obesity is associated with numerous comorbidities including diabetes type 2, peripheral vascular disease, cardiovascular disease, asthma, and osteoarthritis and was shown to be an independent risk factor for developing an end-stage kidney disease (ESKD) [1, 2]. Moreover, the relative risk correlates with a higher body mass index (BMI). The risk of ESKD progression was a
Data Loading...
