Weight loss dynamics following laparoscopic Roux-en-Y gastric bypass. An analysis of 10-year follow-up data
- PDF / 620,266 Bytes
- 7 Pages / 595.276 x 790.866 pts Page_size
- 112 Downloads / 177 Views
and Other Interventional Techniques
2020 SAGES ORAL
Weight loss dynamics following laparoscopic Roux‑en‑Y gastric bypass. An analysis of 10‑year follow‑up data Piotr Gorecki1 · Paul H. McClelland1 · Krystyna Kabata1 · Elizabeth Khusid1 · Michael E. Zenilman1 Received: 7 April 2020 / Accepted: 16 September 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Background Laparoscopic Roux-en-Y gastric bypass (LRYGB) still remains the gold-standard bariatric procedure. Shortterm weight loss and improvement of type 2 diabetes mellitus (DM2) after LRYGB are well-documented. Little data are available on long-term weight loss and continued remission of DM2 in these patients. Methods This study reports on weight loss and remission of DM2 in 576 consecutive patients who underwent primary LRYGB between August 2001 and August 2009 with at least 10-year follow up. All patients were treated at a single institution by a single surgeon. All data were collected and entered into the database prospectively. Results A total of 576 patients were included in the study. Patients’ mean age was 38.2 ± 10.9 years and females represented 88.2% of patients. Patients’ ethnicity was diverse, including African Americans (44.4%), Caucasians (34.0%), Hispanics (18.1%), and 3.5% from other backgrounds. On average, there were 6.9 ± 2.7 comorbidities per patient and DM2 was initially present in 150/576 patients (26.0%). Mean preoperative weight and BMI were 132.4 ± 22.0 kg and 48.3 ± 6.7 kg/m2, respectively. Ten-year follow-up reporting rate was 145/576 (25.2%). Maximum weight loss occurred at 18 months (mean weight 83.4 ± 16.5 kg, mean BMI 30.5 ± kg/m2). At 10 years, mean weight was maintained at 94.8 ± 20.5 kg and mean BMI was 34.3 ± 6.8 kg/m2. The average weight regain between one and ten years was 8.27 kg. Among patients with preoperative DM2, continued remission of DM2 at 10 years occurred in 19/32 (59.4%) patients. Conclusions LRYGB provides durable long-term weight loss, as well as successful remission of DM2 at 10 years. More long-term follow-up studies evaluating weight loss and comorbidities extending beyond the initial 10-year period are needed. Such studies are essential for projecting late outcomes of LRYGB, particularly in younger patients with life expectancy exceeding several decades. Keywords Weight loss · Roux-en-Y gastric bypass · Bariatric surgery · Laparoscopic surgery · Diabetes Morbid obesity has reached an epidemic proportion and has become an increasingly challenging public health issue. It has been reported that 42.4% of the adult US population is obese and the prevalence of morbid obesity has reached 9.2% [1]. It has been widely recognized that obesity and metabolic disease result in increased morbidity and significant reduction of quality of life and overall life expectancy [2, 3]. Dietary and lifestyle modifications alone produce poor results since long-term patient compliance with conservative programs is rare [2–4]. In contrast, bariatric surgery has * Piotr Gorecki pgorecki4@gmai
Data Loading...
