Years of Life Lost from Lung, Stomach, Liver and Cervical Cancers: An Evaluation of the Top Cancer Killers
Based on GLOBOCAN 2002 data, lung, stomach, and liver cancers are the top three cancer killers in both sexes worldwide; cervical cancer is the third most common cause of deaths from cancer among women globally and the top cancer killer among women in dev
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Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 826
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What Are ‘‘Years of Life Lost?’’ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 827
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Data Sources . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 827
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Years of Life Lost Calculation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 828
5 5.1 5.2 5.3 5.4
Years of Life Lost Burden . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 828 Lung Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 829 Stomach Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 833 Liver Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 834 Cervical Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838
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Controversy Surrounding Years of Life Lost . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 839
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Additional Considerations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 839
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Conclusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 840 Summary Points . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 840
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Springer Science+Business Media LLC 2010 (USA)
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Years of Life Lost from Lung, Stomach, Liver, and Cervical Cancers
Abstract: Based on > GLOBOCAN 2002 data, lung, stomach, and liver cancers are the top three cancer killers in both sexes worldwide; cervical cancer is the third most common cause of deaths from cancer among women globally and the top cancer killer among women in developing countries. In this evaluation the burden of lung, stomach, liver, and cervical cancers are assessed using the > years of life lost (YLL) measure, which accounts for both the number of deaths and the age at which death occurs. World mortality data for lung, stomach, liver, and cervical cancers was obtained from GLOBOCAN 2002 by region and sex. Poisson regression models were used to interpolate mortality rates by five-year age categories from the broader GLOBOCAN categories. YLLs were calculated using a model with nonuniform age weights and a > discount rate of 3%. Each year, lung, stomach, liver, and cervical cancers are r
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