• PDF / 169,499 Bytes
• 1 Pages / 595.245 x 841.846 pts (A4) Page_size
• 1 Downloads / 189 Views

DOWNLOAD

REPORT

---

1 S

Cholecystitis: case report A 66-year-old man developed cholecystitis following treatment with yttrium-90 as selective internal radiation therapy (SIRT) for liver metastasis. The man, whose history was notable for colonic adenocarcinoma with liver metastasis, presented with complaints of right upper quadrant pain. An ultrasound revealed gallstones. The man was conservatively treated. However, his symptoms were not controlled. Therefore, he was hospitalised and underwent cholecystectomy. Haematoxylin-eosin-stained tissue sections from his gallbladder showed acute and chronic cholecystitis with focal erosion and some epithelial atypia. Multiple characteristic, black, spherical yttrium-90 [90Y] SIRT microspheres were visualised in intravascular and extravascular sites. They were observed in association with a histiocytic response and mixed inflammatory infiltrate, comprising plasma cells, lymphocytes and eosinophils. A review of his history revealed that he had undergone radioembolisation therapy with yttrium-90 [route and dosage not stated] for liver metastasis, approximately 6 weeks before the development of upper quadrant pain. The epithelial atypia was thought to be radiation-induced atypia. Pantaleon Vasquez R, et al. Yttrium-90 Microsphere Selective Internal Radiation Therapy-Induced Cholecystitis. International Journal of Surgical Pathology 28: 649-650, No. 803497344 6, Sep 2020. Available from: URL: http://doi.org/10.1177/1066896919892589

0114-9954/20/1818-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved

Reactions 22 Aug 2020 No. 1818