12.25 Aortic Stiffness: a Reversible Marker of Cardiovascular Risk in Primary Hyperparathyroidism?
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High Blood Press Cardiovasc Prev 2008; 15 (3): 171-215 1120-9879/08/0003-0171/$48.00/0 © 2008 Adis Data Information BV. All rights reserved.
Vessels and Endothelium 12.25 Aortic Stiffness: a Reversible Marker of Cardiovascular Risk in Primary Hyperparathyroidism? G. Pucci, M.R. Mannarino, N. Avenia, M. Monacelli, G. Fabbriciani, M. Pirro, A.M. Scarponi, E. Mannarino, G. Schillaci ` di Perugia, Medicina Interna, Angiologia e Malattie da Arteriosclerosi, Universita Perugia, Italy Introduction. Patients with primary hyperparathyroidism (PHPT) are at increased risk of cardiovascular death. We investigated whether aortic stiffness, an early marker of arteriosclerosis (Study A) is increased in PHPT and (Study B) improves after parathyroidectomy. Results. Study A: 19 patients with PHPT (age 57±11 years, BP 149/89 mmHg) and 38age-, sex- and blood pressure-matched control subjects underwent aortic pulse wave velocity (PWV) determination (tonometry). Aortic PWV was significantly higher among PHTP patients(11.3±2 vs 9.7±2 m/s, p
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