2019-nCoV: a worldwide concern and facts

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REVIEW ARTICLE

2019-nCoV: a worldwide concern and facts Rajani Sharma1



Gargi Akhoury2

Received: 5 May 2020 / Accepted: 24 September 2020 Ó Indian Virological Society 2020

Abstract A recent outbreak of endemic disease speeded by a virus whose genome is similar to that of SARS and MERS which outbreak in 2002 and 2012 respectively. All these are zoonotic infection which means these has transmitted from animal to human. Another similarity amongst these infections is that bat is supposed to be primary reservoir for these viruses. 2019-nCoV was reported by WHO on 31 December 2020 which is spreading with alarming rate. WHO has considered this infection as pandemic which means that if the infection is misled then it will spread fear and will cause unnecessary suffering and death. The onset of infection shows general symptoms of flu which later on develops to pneumonia. The main challenge of the infection is that a defined vaccine or medicine is still under trial. Treatment is done on the basis of symptoms and recovery is dependent on the immune response of the patients. This review article is based on meta-analysis of the data where the relation between reproduction number (R0) and infection rate is well depicted. Most of the countries has R0 [ 1 which says the infection is epidemic. Symptoms and possible treatment till date is well defined in this paper. Though the COVID-19 virus has changed its strain and came up with asymptomatic infection which is more challenging. Here we

& Rajani Sharma [email protected]; [email protected] Gargi Akhoury [email protected] 1

Amity Institute of Biotechnology, Amity University Jharkhand, Niwaranpur, Ranchi 834002, India

2

Amity School of Engineering and Technology, Amity University Jharkhand, Niwaranpur, Ranchi 834002, India

present all the relevant information and facts about novel corona virus. Keywords 2019-nCoV  Zoonotic disease  Epidemic  Pandemic  Reproduction number

Introduction These days a novel coronavirus which belongs to Severe Acute Respiratory Syndrome (SARS) and Middle East respiratory syndrome (MERS) family has become a pandemic worldwide and named as 2019-nCoV. Its spread rate is alarming and has thus been classified as a social as well as an economic concern. Lack of knowledge is creating panic and difficulty to take steps against its infectious rate. Corona has emerged as epidemical disease. It has originated from Wuhan, Hubei Province, in the month of December through direct exposure to the seafood and animal market [33, 2] and spreading through contact at alarming rate. It spread through contact in four different stages. In stage-1, there is transmission of disease from animal to human or it can invade nearby area by migration of infected people. As in China human got the infection from animals and because of their migration it invaded to other counties too. In stage-2, infection is transmitted through contact from one person to another which is known as local transmission. Till stage-2 it is easy to control the infection but as inf