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(2020) 18:425 Forero et al. J Transl Med https://doi.org/10.1186/s12967-020-02596-2

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A brief guide to the science and art of writing manuscripts in biomedicine Diego A. Forero1,2*, Sandra Lopez‑Leon3*  and George Perry4

Abstract  Publishing articles in international scientific journals is the primary method for the communication of validated research findings and ideas. Journal articles are commonly used as a major input for evaluations of researchers and institutions. Few articles have been published previously about the different aspects needed for writing high-quality articles. In this manuscript, we provide an updated and brief guide for the multiple dimensions needed for writing manuscripts in the health and biological sciences, from current, international and interdisciplinary perspectives and from our expertise as authors, peer reviewers and editors. We provide key suggestions for writing major sections of the manuscript (e.g. title, abstract, introduction, methods, results and discussion), for submitting the manuscript and bring an overview of the peer review process and  of the post-publication impact of the articles. Keywords:  Peer review, Abstracting and indexing, Publications, Writing, Biological science disciplines Introduction Publishing articles in international scientific journals is the current primary approach for the communication of validated research findings and ideas. Scientific papers are commonly used as a major input for evaluations of researchers and institutions [1, 2]. However, taking into account the evolving and multidimensional landscape of the publishing process, there is a need for additional updated training in the science and art of writing manuscripts for scientific journals. Few articles have been published previously about the different aspects needed for writing high-quality articles [3–6]. In this article, we provide an updated and brief guide for the multiple dimensions needed for writing manuscripts in the health and biological sciences, from current, international and interdisciplinary perspectives and from our expertise as authors, peer reviewers and editors, extending and complementing previous *Correspondence: [email protected]; [email protected] 1 Health and Sport Sciences Research Group, School of Health and Sport Sciences, Fundación Universitaria del Área Andina, Bogotá, Colombia 3 Global Drug Development, Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA Full list of author information is available at the end of the article

publications about this topic. The writing of manuscripts in biomedicine has its own standards, including the availability of multiple guidelines for reporting different types of studies, which are discussed in this article.

General recommendations One of the first steps before starting to write an article should be to read the main papers that have been previously published on the subject. The first search might be focused on the available literature reviews and metaanalyses, and key for a sci