A case of gastrointestinal stromal tumor with spontaneous rupture in the greater omentum
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BioMed Central
Open Access
Case report
A case of gastrointestinal stromal tumor with spontaneous rupture in the greater omentum Norihiro Yoshimura1, Hirotaka Ohara*2, Katsuyuki Miyabe1, Tessin Ban1, Hitoshi Sano1, Itaru Naitoh2, Kazuki Hayashi2, Tomoaki Ando2, Takahiro Nakazawa2 and Takashi Joh2 Address: 1Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, 5-161 Maehatacho, Tajimi, Gifu, 507-8522, Japan and 2Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho, Nagoya, Aichi, 4678601, Japan Email: Norihiro Yoshimura - [email protected]; Hirotaka Ohara* - [email protected]; Katsuyuki Miyabe - [email protected]; Tessin Ban - [email protected]; Hitoshi Sano - [email protected]; Itaru Naitoh - [email protected]; Kazuki Hayashi - [email protected]; Tomoaki Ando - [email protected]; Takahiro Nakazawa - [email protected]; Takashi Joh - [email protected] * Corresponding author
Published: 29 July 2008 International Seminars in Surgical Oncology 2008, 5:19
doi:10.1186/1477-7800-5-19
Received: 27 September 2007 Accepted: 29 July 2008
This article is available from: http://www.issoonline.com/content/5/1/19 © 2008 Yoshimura et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: Although GIST generally occurs in the digestive tract, such as the stomach, and small and small intestine primarily, Omental GIST tumours are very rare. Case Presentation: A 63-year-old male patient, who recognized an abdominal tumor 1 year before admission, had a slight expansion of the tumor, reduction of the body and malaise, was consulted to our hospital. Abdominal CT and MRI revealed a cystic lesion of 26 cm in diameter with a clear boundary from immediately below the interseptum to the pelvic cavity, and imaged the septum and cystic wall. We considered that the patient had a cystic tumor in the abdomen, of which the primary lesion was unknown, and scheduled surgery. The patient unfortunately deteriorated with shock and sudden pain in the abdomen. Wediagnosed tumor rapture, and emergency surgery was performed. The tumor, weighing 3,600 g, was mostly cystic, and filled with sanguinous fluid and clot. Histologically, the tumor was composed of spindle cells, and was positive for c-KIT (CD117), slightly positive for alpha-smooth muscle actin (SMA), and S-100 protein positive. Based on these findings, the tumor was diagnosed as GIST primarily occurring in the greater omentum. Conclusion: We experienced a rare case of GIST which originated from the greater omentum. Recently, the prognosis of GIST has been improved since the treatment with Imatinib. It is necessary to consider the diag
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