A case report of bronchial pleomorphic adenoma in a child in China
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CASE REPORT
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A case report of bronchial pleomorphic adenoma in a child in China Haiqin Zhong, Silei Yan, Kung Jiang, Yijing Hu and Xiaoyan Dong*
Abstract Background: Paediatric cases of pleomorphic adenoma of the bronchus are rare in clinical practice, despite pleomorphic adenoma being the most common histological form of salivary gland neoplasm. To date, no such cases have been reported in China. Case presentation: We report a case of pleomorphic adenoma of the bronchus in a 10-year-old child with no obvious positive signs on examination. Chest-enhanced computed tomography and bronchoscopy showed a large white mass in the right principal bronchus. The patient was treated by bronchial mass resection. Biopsy confirmed the diagnosis of pleomorphic adenoma. Conclusions: We not only describe a rare benign bronchial tumour in children but also demonstrate the successful use of surgery as a radical cure for pleomorphic adenoma. Keywords: Pleomorphic adenoma, Bronchus, Child, Case report
Background Pleomorphic adenoma, also called mixed tumour, salivary gland type, is the most common benign tumour of the salivary glands, most frequently occurring in the parotid gland (approximately 80%), followed by the jaws, submandibular gland, sublingual gland, cheeks, mouth, and lips [1]. Paediatric cases of pleomorphic adenoma of the bronchus are rare in clinical practice and are easily missed during diagnosis and misdiagnosed due to their slow growth and nonobvious symptoms in the early stage [2]. To date, no such cases have been reported in China. Due to the rarity of intrabronchial pleomorphic adenoma, no formal study has described its treatment or provided long-term follow-up results. The main treatments include surgical resection and bronchoscopic interventional therapy. We report a case of bronchial pleomorphic adenoma, which was successfully removed by surgery.
* Correspondence: [email protected] Department of Respiratory Medicine, Children’s Hospital of Shanghai, Shanghai Jiao Tong University, Shanghai, China
Case presentation A 10-year-old boy was admitted to the other hospital because of coughing for 7 days 1 month ago and had undergone a chest computed tomography scan. The scan revealed a 1.3-cm mass occupying the right main bronchus and atelectasis in the upper lobe of the right lung. Bronchoscopy and biopsy were performed 12 days after the computed tomography scan. Bronchoscopy showed hyperplasic tissue in the right main bronchus. Pathology showed incisional hypersensitivity and hyperplasia of the right bronchus. Chronic inflammation of the bronchial mucosa was observed. The epithelial cells of the mucosa were proliferated and squamous, with some papillary hyperplasia. After the child was admitted to our hospital, no obvious positive signs were observed during physical examination. An enhanced computer tomographic scan was conducted, which showed a mass occupying the right main bronchus and obstructive pneumonia with atelectasis, as shown in Fig. 1. We also performed another bronchoscopy, which showed t
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