A comparison of EQ-5D index scores using the UK, US, and Japan preference weights in a Thai sample with type 2 diabetes
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A comparison of EQ-5D index scores using the UK, US, and Japan preference weights in a Thai sample with type 2 diabetes Phantipa Sakthong*1, Rungpetch Charoenvisuthiwongs2 and Rossamalin Shabunthom3 Address: 1Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand, 2Department of Pharmacy Administration, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand and 3Sawangdandin Crown Prince Hospital, Sakolnakorn, Thailand Email: Phantipa Sakthong* - [email protected]; Rungpetch Charoenvisuthiwongs - [email protected]; Rossamalin Shabunthom - [email protected] * Corresponding author
Published: 23 September 2008 Health and Quality of Life Outcomes 2008, 6:71
doi:10.1186/1477-7525-6-71
Received: 4 February 2008 Accepted: 23 September 2008
This article is available from: http://www.hqlo.com/content/6/1/71 © 2008 Sakthong et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: Data are scarce on the comparison of EQ-5D index scores using the UK, US, and Japan preference weights in other populations. This study was aimed to examine the differences and agreements between these three weights, psychometric properties including test-retest reliability, convergent and known-groups validity, and the impact of differences in the EQ-5D scores on the outcome of cost-utility analysis in Thai people. Methods: A convenience sample of 303 type 2 diabetic outpatients (18 years or older) from a cross-sectional study was examined. ANOVA and pos-hoc Bonferroni tests were used to determine the differences among the three EQ-5D scores. The agreements among the EQ-5D scores were assessed employing intraclass correlations coefficients (ICCs) and Bland-Altman plots. The ICCs were utilized to examine the test-retest reliability. Spearman's rho correlation coefficients were used to assess the convergent validity between the EQ-5D scores and sociodemographic & clinical data, and health status. Mann-Whitney U tests were used to test the differences in EQ-5D scores between the known groups including HbA1c level (cut point of 7%), and the presence of diabetic complications namely neuropathy, retinopathy, nephropathy and cardiovascular diseases. Seven hypothetical decision trees were created to evaluate the impact of differences in the EQ-5D scores on the incremental cost-utility ratio (ICUR). Results: The US weights yielded higher scores than those of the UK and the Japan weights (p < 0.001, both), while the UK and the Japan weighted scores did not differ (p > 0.05). Both UK and US scores had more agreement with each other than with the Japan scores. Regarding psychometric properties, the Japan scheme provided better test-retest reliability, convergent a
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