A critical appraisal of surgical outcomes following orbital hypertelorism correction: what is the incidence of true bony

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A critical appraisal of surgical outcomes following orbital hypertelorism correction: what is the incidence of true bony relapse versus soft tissue telecanthus? Beatrice C. Go 1 & Sameer Shakir 2

&

Jordan W. Swanson 3 & Scott P. Bartlett 3 & Jesse A. Taylor 3

Received: 7 August 2020 / Accepted: 15 September 2020 # Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Background Orbital hypertelorism (OHT) represents a congenital condition defined by lateralization of the bony orbit, unlike soft tissue telecanthus in which there is an increase in intercanthal distance without true bony lateralization. Existing literature remains very limited in its postoperative assessment of bony versus soft tissue relapse, which may both clinically present as telecanthus. We performed a critical appraisal of the literature to determine the postoperative incidence of bony versus soft tissue relapse following OHT repair. Methods The PubMed, MEDLINE, EMBASE, Scopus, Cochrane Central Register of Controlled Trials, and clinicaltrials.org were searched systematically for all English studies published in any time frame reporting relapse rates following primary OHT repair. The primary outcome was incidence of bony and soft tissue relapse defined as orbital lateralization and medial canthal drift, respectively. The secondary outcome measures include postoperative complications, predictors of postoperative complications, timing and type of surgery, and revision rates. Results Eleven articles were included. A total of 84 (35.3%) patients experienced bony relapse while 43 (27.2%) patients experienced soft tissue relapse. Age at time of intervention (p < 0.92), severity at presentation (p < 0.90), and surgical technique (p < 0.09) were not found be significantly associated with relapse rate. Methods for long-term follow-up were not standardized, and there was no consistent measure to objectively assess telecanthus. Conclusions There is no general consensus on predictive factors of long-term relapse following OHT repair in the form of box osteotomy or facial bipartition. These findings call for cross-sectional outcome standardization to better understand long-term outcomes across institutional, provider, and patient differences. Keywords Orbital hypertelorism . Bony relapse . Canthopexy . Telecanthus . Box osteotomy . Facial bipartition

Introduction Beatrice C. Go and Sameer Shakir contributed equally to this work. Electronic supplementary material The online version of this article (https://doi.org/10.1007/s00381-020-04890-2) contains supplementary material, which is available to authorized users. * Jesse A. Taylor [email protected] 1

Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

2

Division of Plastic and Reconstructive Surgery, Hospital of University of Pennsylvania, Philadelphia, PA, USA

3

Division of Plastic and Reconstructive Surgery, Children’s Hospital of Philadelphia, Philadelphia, PA, USA

The term “ocular hypertelorism” was first described by David Greig in 1924