A Practical Guide to Drug Development in Academia The SPARK Approach
"A lot of hard-won knowledge is laid out here in a brief but informative way. Every topic is well referenced, with citations from both the primary literature and relevant resources from the internet." Review from Nature Chemical BiologyWritten by the foun
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Daria Mochly-Rosen Kevin Grimes Editors
A Practical Guide to Drug Development in Academia The SPARK Approach 123
SpringerBriefs in Pharmaceutical Science & Drug Development
For further volumes: http://www.springer.com/series/10224
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Daria Mochly-Rosen • Kevin Grimes Editors
A Practical Guide to Drug Development in Academia The SPARK Approach
Editors Daria Mochly-Rosen Kevin Grimes Department of Chemical and Systems Biology Stanford University School of Medicine Stanford, California USA
ISSN 1864-8118 ISSN 1864-8126 (electronic) ISBN 978-3-319-02200-0 ISBN 978-3-319-02201-7 (eBook) DOI 10.1007/978-3-319-02201-7 Springer Cham Heidelberg New York Dordrecht London Library of Congress Control Number: 2013951226 © The Editors 2014 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
We dedicate this book to our SPARKees–Stanford faculty, postgraduate fellows, and students who have stepped beyond the confines of traditional academia to embrace the challenges of drug discovery and development. We are inspired by your efforts to translate your discoveries into new treatments that will benefit patients, and we have learned a great deal from each of you.
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Preface
Our intention in putting together this volume, A Practic
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