A study on the change of droplet volume by the increase of flow rate

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A study on the change of droplet volume by the increase of flow rate Kunio Horiuchi1  Received: 20 March 2020 / Accepted: 27 August 2020 © Springer Nature Switzerland AG 2020

Abstract Drip-control type infusion pumps cause a flow rate error when the volume of the droplet dropping in the drip chamber changes. Therefore, the purpose of this study is to accurately measure the volume of one droplet as the flow rate increases. For measurement of droplet volume, a droplet bypassing device was prototyped. In the case of a 20 drop/mL drip nozzle, a volume error of + 7.6% occurred at a flow rate of 500 mL/min, compared to the theoretical volume of 50.0 mm3. In the case of a 60 drop/mL drip nozzle, a volume error of − 17.4% occurred at a flow rate of 300 mL/min, compared to the theoretical volume of 16.7 mm3. Moreover, the standard deviation of the measured value of the droplet volume increased as the flow rate increased. It was shown that even with proper use of the infusion set, significant flow rate errors can occur depending on the flow rate settings. Therefore, it is considered that the drip-control type infusion pump needs to be controlled by correcting the volume change due to the increase in the flow rate.

*  Kunio Horiuchi, [email protected] | 1Department of Mechanical Science and Engineering, School of Advanced Engineering, Kogakuin University, 2665‑1, Nakano‑cho, Hachioji‑shi, Tokyo 192‑0015, Japan. SN Applied Sciences

(2020) 2:1603

| https://doi.org/10.1007/s42452-020-03448-w

Vol.:(0123456789)

Research Article

SN Applied Sciences

(2020) 2:1603

| https://doi.org/10.1007/s42452-020-03448-w

Graphic Abstract The volume of one droplet intermittently dropped from the drip nozzle using a droplet bypass device was accurately measured. The change in droplet volume with increasing flow rate was shown

drip nozzle

photo interrupter

drip catcher

droplet (a) Droplet dropped on electronic balance

bypass channel

(b) Droplet flows into the bypass channel

Schematic diagram of operation of droplet bypass device. The change in droplet volume when using a 20drop/1mL drip nozzle. test liquid back drip nozzle mounting part droplet bypass device bypass device controller

test liquid replenishment pump

electronic balance three-way stopcock

Photograph of measuring system

The change in droplet volume when using a 60drop/1mL drip nozzle.

Keywords  Infusion pump · Drip-control · Droplet volume · Droplet bypassing device · Drip nozzle

1 Introduction Infusion pumps are one of the most frequently used medical devices in hospitals. There are a drop control method and a volume control method as the flow control methods of the linear peristaltic infusion pump. In the case of the drop control method, the number of droplets dropped in the drip chamber is counted for a fixed time, and feedback control is performed in comparison with the set flow rate. ISO 8536-4 defines only two drop rates, 20 drop/1 mL and 60 drop/1 mL. However, the volume of a drop may change under various conditions. One of these causes may be the l