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Soft Tissue Tumors

Simone Mocellin

Soft Tissue Tumors A Practical and Comprehensive Guide to Sarcomas and Benign Neoplasms

Simone Mocellin Department of Surgery Oncology and Gastroenterology University of Padova Padova Italy Melanoma and Soft Tissue Sarcoma Unit Istituto Oncologico Veneto (IOV-IRCCS) of Padova Padova Italy

ISBN 978-3-030-58709-3    ISBN 978-3-030-58710-9 (eBook) https://doi.org/10.1007/978-3-030-58710-9 © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2021 This work is subject to copyright. All rights are solely and exclusively licensed by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

To my son Michele and my wife Marta, for their infinite love and constant support

Preface

Soft tissue tumors are a heterogeneous group of more than 200 nosological entities that include both benign neoplasms and malignant neoplasms (i.e., soft tissue sarcomas), can affect people of any age, and can arise in virtually any site of the human body. Given the number of these tumors (which is often multiplied by a variety of clinicopathological subtypes), the epidemiological rarity of most of them, and the plethora of synonyms often utilized to refer to them, the topic of soft tissue neoplasms results complex and remembering the details on epidemiologic, clinical, pathologic, molecular, prognostic, and therapeutic details of each single entity is intrinsically challenging. The aim of this book is to provide readers with a friendly, practical, and comprehensive guide to navigate in this complex area of oncology, bringing together the essential and most updated information on the following aspects of each tumor: –– Definition: Tumor name, as per World Health Organization (WHO) classific