Adherence to the Mediterranean diet is associated with decreased fecal calprotectin in patients with ulcerative colitis
- PDF / 1,200,465 Bytes
- 8 Pages / 595.276 x 790.866 pts Page_size
- 71 Downloads / 245 Views
ORIGINAL CONTRIBUTION
Adherence to the Mediterranean diet is associated with decreased fecal calprotectin in patients with ulcerative colitis after pouch surgery L. Godny1 · L. Reshef2 · T. Pfeffer‑Gik1 · I. Goren1 · H. Yanai1 · H. Tulchinsky3 · U. Gophna2 · I. Dotan1 Received: 25 September 2019 / Accepted: 29 November 2019 © Springer-Verlag GmbH Germany, part of Springer Nature 2019
Abstract Background Mediterranean diet (MED) is associated with health benefits, yet scarce data exist regarding the role of MED in inflammatory bowel diseases (IBD). Herein, we aimed to evaluate the association between MED and inflammatory markers in patients with IBD after pouch surgery. Methods Consecutive patients after pouch surgery due to ulcerative colitis (UC) were recruited at a comprehensive pouch clinic. Adherence to MED was calculated according to MED score, ranging from 0 (low adherence) to 9 (high adherence), based on food-frequency questionnaires. Pouch behavior was defined as normal pouch (NP) or pouchitis based on Pouchitis Disease Activity Index (PDAI) and disease activity was defined as active or inactive. C-reactive protein (CRP) and fecal calprotectin were assessed. Results Overall 153 patients were enrolled (male gender 47%; mean age 46 ± 14 years; mean pouch age 9.5 ± 7 years). MED scores were higher in patients with normal vs. elevated CRP and calprotectin levels (4.6 ± 1.8 vs. 4.4 ± 1.6, p = 0.28; 4.8 ± 1.8 vs. 4.07 ± 1.7, p
Data Loading...
