Advancements of Mass Spectrometry in Biomedical Research
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Alisa G. Woods Costel C. Darie Editors
Advancements of Mass Spectrometry in Biomedical Research Second Edition
Advances in Experimental Medicine and Biology Volume 1140
Editorial Board Member: IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA JOHN D. LAMBRIS, University of Pennsylvania, Philadelphia, PA, USA RODOLFO PAOLETTI, University of Milan, Milan, Italy NIMA REZAEI, Tehran University of Medical Sciences, Children’s Medical Center Hospital, Tehran, Iran
More information about this series at http://www.springer.com/series/5584
Alisa G. Woods • Costel C. Darie Editors
Advancements of Mass Spectrometry in Biomedical Research Second Edition
Editors Alisa G. Woods Biochemistry and Proteomics Group Department of Chemistry and Biomolecular Science Clarkson University Potsdam, NY, USA
Costel C. Darie Biochemistry and Proteomics Group Department of Chemistry and Biomolecular Science Clarkson University Potsdam, NY, USA
ISSN 0065-2598 ISSN 2214-8019 (electronic) Advances in Experimental Medicine and Biology ISBN 978-3-030-15949-8 ISBN 978-3-030-15950-4 (eBook) https://doi.org/10.1007/978-3-030-15950-4 © Springer Nature Switzerland AG 2014, 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
To Professor Dr. Vlad Artenie (University of Iasi, Romania), to late Professor Dr. Wolfgang Haehnel (University of Freiburg, Germany), and to Dr. Kenneth R. Woods, an inspirational biochemist. Also, to the past and current members of Darie Lab, as well as to its many supporters.
Preface
The use of mass spectrometry (MS) is becoming increasingly important for biomedical research and for clini
