Adverse reaction of pharmacopuncture treatment in Korea: a literature review
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RESEARCH ARTICLE
Adverse reaction of pharmacopuncture treatment in Korea: a literature review Kyeong Han Kim1 Received: 4 December 2019 / Accepted: 21 February 2020 © Institute of Korean Medicine, Kyung Hee University 2020
Abstract The aim of this study was to investigate clinical adverse reaction of pharmacopuncture. It was searched in four Korean database that case report or case series study related to pharmacopuncture since 2000. Among them, studies reported adverse reaction was selected. The characteristics, types of pharmacopuncture, adverse reaction patterns, follow-up were investigated separately. A total of 10 studies and 17 cases reported adverse reactions after pharmacopuncture treatment. The mean age was 45 ± 12.1 years and musculoskeletal system diseases (47.1%) and neurological diseases (41.2%) were most common. Bee venom (58.8%) and Bufonis Venenum (17.6%) accounted for most of the adverse reactions. And symptom also appeared to be serious, such as dizziness, seizure, unconsciousness, nausea, and dyspnea. Adverse reaction were also seen in CarthmiFlos, Horminis Placenta, and Juglandis Semen. But symptoms were minor, such as uredo and rash and it disappeared within 24 h after treatment. There is a need to establish institutional procedures for enhanging safety of pharmacopuncture. Keywords Pharmacopuncture · Bee venom · Bufonis venenum · Adverse reaction
Introduction Pharmacopuncture is a traditional medical treatment combining acupuncture and herbal medicine (Korean Pharmacopuncture Institute 2012). Unlike conventional acupuncture, pharmacopuncture offers the benefits of both acupuncture and herbal medicine, as medicinal agents are injected directly into acupoint sites (Lee et al. 2007). In Korea, pharmacopuncture was first introduced by Sang-Cheon Nam in 1967 and its widespread use began when the Korean Institute of Pharmacopuncture was established in 1990. Currently, The College of Korean Medicine teaches pharmacopuncture as a standard class (Publication Committee on the Yearbook of Traditional Korean Medicine 2018). As a result, 67.4% of Korean medical doctors now use pharmacopunctures in their treatment (Park and Kim 2017).
* Kyeong Han Kim [email protected] 1
Department of Preventive Medicine, College of Korean Medicine, Woosuk University, 61, Seoneomeo 3‑gil, Wansan‑gu, Jeonju‑si, Jeollabuk‑do 54986, Republic of Korea
Pharmacopuncture was first introduced in China, where the pharmacopuncture solution is extracted based on Korena medicine prescriptions. It is mainly used in the form of intravenous injections and is administered in a similar manner to injections produced by pharmaceutical companies (National Development Institute of Korean Medicine 2017). In Korea, however, the pharmacopuncture solution is generally prepared and used according to the personal preparation method of the Korean medical doctor administering the solution (Korean Pharmacopuncture Institute 2012). As there is a lack of standardization in the preparation of pharmacopuncture solutions in Korea, the issue of
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