Age-related Macular Degeneration Diagnosis and Treatment
Age-related Macular Degeneration Diagnosis and Treatment provides —for the retina specialist, general eye care professional, vision scientist, and those training in these areas—an update on the current understanding of age-related macular degeneration (AM
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Allen C. Ho • Carl D. Regillo Editors
Age-related Macular Degeneration Diagnosis and Treatment
Editors Allen C. Ho, MD, FACS Wills Eye Institute Thomas Jefferson University Philadelphia, PA, USA [email protected]
Carl D. Regillo, MD, FACS Wills Eye Institute Thomas Jefferson University Philadelphia, PA, USA [email protected]
ISBN 978-1-4614-0124-7 e-ISBN 978-1-4614-0125-4 DOI 10.1007/978-1-4614-0125-4 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011932176 © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Foreword
Few ocular diseases are so prevalent and devastating to daily life as age-related macular degeneration (AMD). Yet, very little is known about is pathogenesis and treatment. Given the expanding geriatric population, AMD is assuming epidemic proportion, prioritizing the disorder at the pinnacle of critical medicalretinal disease in need of better management. Fortunately, considerable research has made notable advances in attempting to unravel the biochemical, immunologic, epidemiological and genetic complexities associated with this maculopathy. As a result, there is a wealth of burgeoning knowledge, led by discoveries in molecular biology, genetics, biochemical vasogenic and atrophic pathways, and imaging technology, which specifically displays the microabnormalities related to its pathogenesis. Many of these advances have also led to new opportunities for improved treatment modalities with a better visual prognosis than in the past. It is important to recall that knowledge in any field of medicine relates to a point in time, particularly for a complex disease such as AMD which is constantly under investigation which has led to converging lines of experimental and clinical evidence that modifies established ideas and new treatment concepts. Over the course of years, several comprehensive textbooks and atlases have b
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