Allergy Prevention and Exacerbation The Paradox of Microbial Impact

Allergy is developing into one of the most prevalent diseases affecting individuals in the very early days of life. While the cause of this epidemic is still unclear, it appears that the westernized life style is playing an important role, which includes

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Carsten B. Schmidt-Weber Editor

Allergy Prevention and Exacerbation The Paradox of Microbial Impact on the Immune System

Birkha¨user Advances in Infectious Diseases

Series editors Stefan H.E. Kaufmann Max Planck Institute for Infection Biology, Berlin, Germany Andrew A. Mercer Department of Microbiology and Immunology, University of Otago Dunedin, New Zealand Olaf Weber Bonn, Germany

More information about this series at http://www.springer.com/series/5444

Carsten B. Schmidt-Weber Editor

Allergy Prevention and Exacerbation The Paradox of Microbial Impact on the Immune System

Editor Carsten B. Schmidt-Weber ZAUM Technical University of Munich Munich, Germany

ISSN 2504-3811 ISSN 2504-3838 (electronic) Birkha¨user Advances in Infectious Diseases ISBN 978-3-319-69967-7 ISBN 978-3-319-69968-4 (eBook) https://doi.org/10.1007/978-3-319-69968-4 Library of Congress Control Number: 2017962326 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Contents

Overview: The Paradox of Microbial Impact on the Immune System in Allergy Prevention and Exacerbation . . . . . . . . . . . . . . . . . . Carsten B. Schmidt-Weber Microbial Triggers in Autoimmunity, Severe Allergy, and Autoallergy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Fariza M.S. Badloe, Sherief R. Janmohamed, Johannes Ring, and Jan Gutermuth Bacterial Allergens . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Go´mez-Gasco´n Lidia and Barbara M. Br€oker

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Good and Bad Farming: The Right Microbiome Protects from Allergy . . . . . . . . . . . . . . . . . . . . . .