Amiodarone
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Cryptogenic organising pneumonia: case report A 78-year-old man developed cryptogenic organising pneumonia during treatment with amiodarone for atrial fibrillation. The man had been receiving amiodarone [dosage and route not stated] for atrial fibrillation for 10 years. He presented for CT evaluation of a right apical lung densification. Because of history of chronic cardiac failure and mild renal insufficiency, unenhanced CT was performed. The apical consolidation appeared spontaneously hyperattenuating (65 Hounsfield units [HU]). A right pleural effusion was associated with abnormally hyperattenuating (85HU) partial collapse of the right lower lobe and a hyper-attenuating (100HU) hepatic parenchyma. The hyperattenuating pattern was strongly suggestive of apical amiodarone-induced pneumonitis. A confirmed diagnosis of cryptogenic organising pneumonia was made after lung biopsy [time to reaction onset not stated]. Due to the weakness, corticosteroids were not administered. The man’s treatment with amiodarone was discontinued. Two months following the discontinuation of amiodarone, spontaneous resolution of cryptogenic organising pneumonia was noted, confirming the diagnosis of amiodarone-induced cryptogenic organising pneumonia. Coulier B, et al. Amiodarone-induced cryptogenic organizing pneumonia (COP). Diagnostic and Interventional Imaging 101: 623-625, No. 9, Sep 2020. Available from: URL: 803501475 http://doi.org/10.1016/j.diii.2020.01.004
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Reactions 19 Sep 2020 No. 1822
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